cirrhosis - Nursing Case Study

Pathophysiology

• Primary mechanism: Chronic liver damage leads to inflammation and activation of stellate cells, causing excess collagen deposition and fibrosis. This scarring disrupts normal liver architecture and blood flow.

• Secondary mechanism: The liver becomes unable to perform its vital functions, such as detoxifying blood, producing proteins, and regulating clotting, due to the loss of healthy liver tissue and impaired blood supply.

• Key complication: Portal hypertension develops as scar tissue obstructs blood flow through the liver, leading to increased pressure in the portal vein. This can cause varices, ascites, and increased risk of bleeding.

Patient Profile

Demographics:

56-year-old male, accountant

History:

• Key past medical history: Non-alcoholic fatty liver disease (NAFLD) diagnosed 3 years ago

• Current medications: Ursodeoxycholic acid, vitamin E supplement

• Allergies: None

Current Presentation:

• Chief complaint: Routine follow-up, no acute complaints

• Key symptoms: Mild fatigue, occasional abdominal discomfort

• Vital signs: Blood pressure 118/76 mmHg, heart rate 72 bpm, respiratory rate 16 breaths per minute, temperature 98.6°F, oxygen saturation 98% on room air

Section 1

Initial Assessment Findings:

During the routine follow-up appointment, the nurse conducts a comprehensive initial assessment to evaluate the current status of the patient’s cirrhosis. The patient appears well-nourished and in no acute distress. On physical examination, the nurse notes the presence of mild scleral icterus, suggesting subtle jaundice, which correlates with the patient's known liver dysfunction. The abdomen is soft with slight tenderness in the right upper quadrant, but no significant distension or ascites is observed at this stage. No peripheral edema is present, indicating that fluid retention is minimal. The patient reports mild fatigue and occasional abdominal discomfort, but he denies any significant changes in appetite, weight loss, or gastrointestinal bleeding.

Laboratory results reveal mildly elevated liver enzymes, with ALT and AST levels slightly above the normal range, consistent with ongoing liver inflammation. Bilirubin levels are marginally elevated, corroborating the physical finding of scleral icterus, while albumin and platelet counts remain within normal limits, suggesting preserved synthetic liver function and no immediate risk for significant bleeding. The patient's INR is 1.1, indicating stable clotting function. These findings suggest that while the patient has early-stage cirrhosis with minor complications, the liver is still managing to perform many of its vital functions adequately.

Based on the assessment, the nurse prioritizes patient education and lifestyle interventions aimed at slowing disease progression. Emphasis is placed on maintaining a healthy diet, regular physical activity, and continued adherence to prescribed medications. The nurse also discusses the importance of regular monitoring and follow-up appointments to detect any changes in the patient's condition promptly. This foundational care plan supports the patient’s ability to manage his condition effectively and prepares him for potential changes in his health status that may require further intervention.

Section 2

Several weeks after the initial assessment, the patient returns for a follow-up appointment to monitor his cirrhosis and assess the response to lifestyle modifications and prescribed interventions. The nurse begins the visit by reviewing the patient's self-reported adherence to the recommended dietary changes and medication regimen. The patient reports consistent adherence to a balanced, low-sodium diet and has incorporated gentle daily exercise, such as walking, into his routine. He also confirms taking his medications as prescribed, contributing to his stable condition. The patient notes a slight improvement in energy levels and less frequent episodes of abdominal discomfort, suggesting a positive response to the interventions.

During the physical examination, the nurse observes that the patient's weight has remained stable, and there is no new onset of peripheral edema or abdominal distension. The mild scleral icterus persists, but there is no evidence of worsening jaundice. Vital signs are recorded as follows: blood pressure is 120/78 mmHg, heart rate is 72 beats per minute, respiratory rate is 16 breaths per minute, and temperature is 98.6°F, all within normal limits. These findings indicate that the patient remains in a stable condition with no signs of acute deterioration.

Laboratory results from the recent tests reveal that liver enzymes, ALT and AST, have slightly decreased, indicating a reduction in liver inflammation. Bilirubin levels have stabilized, and both albumin and platelet counts continue to be within normal ranges, reinforcing the conclusion that the liver's synthetic function is still largely preserved. The INR remains at 1.1, suggesting continued stable clotting function. These results reflect the effectiveness of the lifestyle interventions and medication adherence, providing a positive outlook for the patient's management of early-stage cirrhosis. The nurse emphasizes the importance of continuous monitoring and adherence to the care plan to maintain this stable health status and promptly address any future complications.

Section 3

As the follow-up appointment progresses, the nurse takes the opportunity to delve deeper into the patient's response to interventions, focusing on his lifestyle modifications and medication regimen. The patient expresses satisfaction with the current dietary plan and mentions that he has discovered new low-sodium recipes that he enjoys, making adherence easier. He also shares that his daily walks have become a cherished part of his routine, contributing to improved mental well-being and a sense of accomplishment. The nurse applauds these positive lifestyle changes and reinforces the importance of maintaining these habits to support liver health.

Despite the overall stable condition, the patient mentions experiencing occasional episodes of mild pruritus, primarily in the evenings. The nurse recognizes this as a common symptom associated with liver disease and provides reassurance, suggesting practical interventions such as using moisturizing lotions and avoiding hot showers to alleviate discomfort. The nurse also advises the patient to monitor the frequency and intensity of the pruritus, as any escalation could indicate changes in the disease's progression and warrant further evaluation.

As the visit concludes, the nurse and patient collaboratively review the care plan, emphasizing the importance of regular follow-up appointments to monitor liver function and detect any potential complications early. The patient is encouraged to continue his current regimen and is educated on signs and symptoms that should prompt immediate medical attention, such as increased jaundice, significant weight changes, or new onset of confusion. The nurse schedules the next follow-up visit and provides contact information for any interim concerns, ensuring a comprehensive support system is in place as the patient continues to manage his early-stage cirrhosis successfully.

Section 4

Several weeks later, during a scheduled follow-up appointment, the nurse begins with an initial assessment to evaluate the patient’s current condition. The patient appears well-nourished and in good spirits, reflecting the positive impact of his lifestyle modifications. Upon examination, vital signs are stable: blood pressure is 120/78 mmHg, heart rate is 72 beats per minute, respiratory rate is 16 breaths per minute, and temperature is 98.4°F. The patient reports no significant changes in weight, maintaining a steady figure since the last visit. However, he notes that the pruritus has become slightly more frequent, occurring every evening now, though still manageable with the interventions previously suggested.

To ensure a comprehensive evaluation, the nurse reviews recent laboratory results. Liver function tests reveal a slight increase in alanine transaminase (ALT) to 55 U/L and aspartate transaminase (AST) to 48 U/L, slightly above the normal range, indicating mild liver inflammation. Bilirubin levels remain stable at 1.2 mg/dL, and albumin levels are within normal limits at 4.0 g/dL. These findings suggest that while the liver disease remains at an early stage, there is a need for continued monitoring to prevent progression. The nurse discusses these results with the patient, emphasizing the importance of adherence to the prescribed regimen and the potential need for adjustments if symptoms persist or worsen.

The nurse and patient collaboratively decide to increase the frequency of follow-ups to closely monitor any subtle changes in symptoms or lab values. The patient is encouraged to maintain his current lifestyle habits and to contact the healthcare team if he experiences any new symptoms, particularly those that might suggest liver dysfunction, such as fatigue, increased jaundice, or dark urine. This proactive approach aims to address any potential complications early, ensuring the patient remains stable and well-supported on his journey with cirrhosis.

Section 5

Several weeks later, during another follow-up visit, the nurse conducts a routine assessment to evaluate the patient's ongoing condition. The patient continues to appear well-nourished and maintains a positive demeanor, although he mentions feeling slightly more fatigued than usual in the afternoons. Vital signs remain within a stable range: blood pressure is 118/76 mmHg, heart rate is 70 beats per minute, respiratory rate is 16 breaths per minute, and temperature is 98.2°F. Upon further questioning, the patient reports that the pruritus now occurs earlier in the day, but it is still manageable with the current interventions.

The nurse reviews updated laboratory results, noting a slight increase in both ALT and AST levels, with ALT rising to 65 U/L and AST to 55 U/L. Although these levels are still indicative of mild liver inflammation, they suggest a gradual change that requires attention. Bilirubin remains stable at 1.3 mg/dL, and albumin levels are still within normal limits at 4.1 g/dL. The patient's INR is 1.1, indicating that coagulation is within normal limits. These findings highlight the importance of continued monitoring and possibly adjusting the management plan to prevent further liver damage.

In response to these findings, the nurse discusses potential strategies with the patient to address the increasing fatigue and manage liver inflammation. The patient is reminded of the importance of adequate rest and encouraged to monitor for any additional symptoms of liver dysfunction. Together, they decide to slightly modify the patient's diet to include more anti-inflammatory foods and consider mild exercise to improve overall well-being. The nurse schedules more frequent follow-up appointments to ensure close monitoring of the patient's progress and to facilitate timely adjustments to the care plan as needed. This proactive approach aims to sustain the patient's stable condition while addressing the subtle changes in his clinical status.