Alcoholic cirrhosis - Nursing Case Study

Pathophysiology

• Primary mechanism: Chronic alcohol consumption leads to repeated liver cell injury and death. This triggers inflammation and the activation of stellate cells, causing excessive collagen production and scar tissue formation, replacing healthy liver tissue.

• Secondary mechanism: The buildup of scar tissue disrupts blood flow through the liver, increasing pressure in the portal vein (portal hypertension). This pressure can cause blood to bypass the liver, impairing its ability to detoxify and metabolize substances.

• Key complication: Portal hypertension can lead to varices (enlarged veins) in the esophagus and stomach, which are prone to bleeding. Additionally, impaired liver function can result in jaundice, ascites (fluid accumulation in the abdomen), and hepatic encephalopathy (brain dysfunction due to toxins in the blood).

Patient Profile

Demographics:

45-year-old male, construction worker

History:

• Key past medical history: Diagnosed with alcoholic cirrhosis 6 months ago, history of heavy alcohol use for 20 years

• Current medications: Vitamin B complex, ursodeoxycholic acid

• Allergies: No known drug allergies

Current Presentation:

• Chief complaint: Routine follow-up for alcoholic cirrhosis

• Key symptoms: Occasional fatigue, mild abdominal discomfort

• Vital signs: Blood pressure 120/80 mmHg, heart rate 72 bpm, respiratory rate 16 breaths per minute, temperature 98.6°F, oxygen saturation 98% on room air

Section 1

During the initial assessment, the nurse notes that the patient appears well-nourished but exhibits slight scleral icterus, indicating mild jaundice. The patient's skin is free of bruising or petechiae, and there are no signs of ascites upon abdominal palpation. However, there is slight hepatomegaly with mild tenderness in the right upper quadrant, aligning with the patient's occasional reports of abdominal discomfort. The patient's vital signs remain stable, and he denies any recent episodes of gastrointestinal bleeding or changes in stool color, which helps rule out immediate concerns of variceal bleeding.

The nurse also conducts a review of the patient's lifestyle changes since his last visit. The patient reports that he has significantly reduced his alcohol consumption over the past six months and is attending regular counseling sessions to support his sobriety. He acknowledges occasional fatigue, which he attributes to his physically demanding job. The nurse emphasizes the importance of maintaining a balanced diet rich in protein and vitamins while avoiding alcohol, in order to support liver regeneration and overall health.

Based on these findings, the nurse plans to continue monitoring the patient's liver function tests and complete blood count to assess for any emerging complications related to liver function or portal hypertension. The patient is encouraged to follow up regularly for blood tests and ultrasounds to monitor liver size and function. The nurse educates the patient about recognizing symptoms of potential complications, such as increased abdominal swelling, confusion, or signs of gastrointestinal bleeding, which would warrant immediate medical attention. This proactive approach aims to manage the patient's condition effectively while preventing progression to more severe stages of cirrhosis.

Section 2

Three months after the initial assessment, the patient returns for a scheduled follow-up. The nurse notices some changes during the assessment. The patient reports feeling more fatigued than usual, and he has recently observed some discomfort and slight swelling in his ankles by the end of the day. Upon examination, the nurse confirms mild peripheral edema in the lower extremities. The patient's vital signs remain stable, but there is a slight increase in the liver size upon palpation, though still without significant tenderness. The scleral icterus appears to have slightly worsened, indicating a possible progression of the liver dysfunction.

The nurse reviews the most recent laboratory results, which show a mild elevation in liver enzymes, including AST and ALT, compared to the previous readings. The patient's albumin levels have slightly decreased, which could be contributing to the peripheral edema. Additionally, there is a marginal increase in the patient's INR, suggesting the liver's diminished capacity to produce clotting factors, though the patient still denies any active bleeding or bruising. These lab results, along with the clinical findings, suggest the early signs of potential complications from cirrhosis, such as fluid retention and mild coagulopathy.

The nurse discusses these findings with the patient and emphasizes the importance of adhering to dietary recommendations, including a low-sodium diet to manage the edema. The patient is advised to continue avoiding alcohol and to maintain regular attendance at counseling sessions. The nurse also arranges for more frequent monitoring of laboratory values and schedules an ultrasound to assess any further changes in liver size and structure. By reinforcing these interventions and monitoring plans, the nurse aims to manage the progression of the condition while educating the patient on recognizing and responding to potential complications promptly.

Section 3

Two months later, the patient returns for another follow-up appointment, and the nurse observes a change in his condition. The patient reports that he continues to experience fatigue and has noticed an increase in the swelling of his ankles. He describes feeling more bloated and uncomfortable, particularly in the evenings. During the physical examination, the nurse confirms moderate peripheral edema in both lower extremities. The patient's vital signs reveal a slightly elevated blood pressure of 138/86 mmHg, which is a change from previous readings. His heart rate remains stable at 78 beats per minute, and his respiratory rate is 18 breaths per minute, with an oxygen saturation of 97% on room air.

The nurse reviews the latest laboratory results, which indicate further elevation of liver enzymes, with AST at 92 U/L and ALT at 78 U/L. The albumin level has decreased to 2.8 g/dL, reflecting a decline from the previous level, and the INR has increased to 1.4, suggesting a progression in coagulopathy. These lab findings, combined with the patient's symptoms, suggest worsening liver function and an increased risk for complications. The nurse discusses these results with the patient, highlighting the importance of adhering to the treatment plan, including dietary modifications and medication adherence.

To address these developments, the nurse coordinates with the healthcare team to adjust the patient's medication regimen, possibly including diuretics to manage the edema. The patient is advised to continue avoiding alcohol and is encouraged to engage in light physical activity as tolerated to help manage fluid retention. A referral to a dietitian is made to reinforce dietary recommendations, particularly focusing on sodium restriction. The nurse emphasizes the importance of monitoring for signs of ascites and any potential bleeding, instructing the patient to seek medical attention if these symptoms occur. By maintaining a proactive approach, the nurse aims to manage the patient's condition effectively and prevent further complications.

Section 4

Two weeks later, during a scheduled follow-up, the patient reports some improvement in the swelling of his ankles, attributing it to the diuretics prescribed by the healthcare team. However, he mentions a new onset of mild abdominal discomfort and a feeling of tightness around his waist, particularly noticeable after meals. The nurse performs a detailed assessment and notes that while the peripheral edema in the lower extremities has reduced slightly, there is now mild abdominal distension. The patient's weight has increased by 2 kg since the last visit, raising suspicion of fluid retention in the abdomen, potentially indicating early ascites.

The nurse reviews the latest laboratory results, which reveal a further decrease in serum albumin to 2.5 g/dL, exacerbating concerns about the patient's nutritional status and fluid balance. The patient's INR has increased to 1.6, indicating a continued decline in liver function and heightened risk of bleeding. Despite these changes, the patient's vital signs remain relatively stable, with a blood pressure of 136/84 mmHg, a heart rate of 76 beats per minute, and a respiratory rate of 18 breaths per minute. Oxygen saturation remains at 97% on room air.

In response to these findings, the nurse collaborates with the healthcare team to adjust the patient's care plan. The dosage of diuretics is reevaluated and increased to better manage fluid buildup, and the patient is educated on monitoring his weight and abdominal girth at home. The nurse also reinforces dietary recommendations, emphasizing the importance of maintaining a low-sodium diet to help control fluid retention. The patient is encouraged to remain vigilant for any signs of worsening ascites or potential bleeding, such as increased abdominal pain or changes in stool color, and to seek prompt medical attention if these occur. By closely monitoring these developments and adjusting the care plan, the healthcare team aims to stabilize the patient's condition and prevent further complications.

Section 5

During a subsequent follow-up visit two weeks later, the nurse conducts a thorough assessment to evaluate the patient's response to the adjusted care plan. The patient reports that the abdominal discomfort has slightly decreased, and he has been diligent in monitoring his weight and abdominal girth at home. He notes no significant changes in stool color, which is reassuring regarding potential bleeding. During the physical exam, the nurse observes that the abdominal distension has not worsened, and the peripheral edema has further reduced, suggesting some effectiveness of the increased diuretic dosage. However, the patient mentions feeling more fatigued than usual, raising concerns about his overall energy levels and nutritional status.

The nurse reviews the latest laboratory results, which provide additional insight into the patient's condition. The serum albumin level has decreased slightly to 2.4 g/dL, indicating a continued challenge in maintaining adequate protein levels. The INR remains stable at 1.6, still reflecting a risk of bleeding but not worsening. Other liver function tests, such as AST and ALT, show no significant change, suggesting that liver damage, while present, is not rapidly progressing in this early stage of alcoholic cirrhosis. The patient's vital signs remain stable, with a blood pressure of 132/82 mmHg, a heart rate of 74 beats per minute, and a respiratory rate of 18 breaths per minute. Oxygen saturation is consistent at 97% on room air.

Based on these findings, the healthcare team decides to continue monitoring the patient's condition closely, with a focus on optimizing nutritional support. The nurse collaborates with a dietitian to develop a tailored nutrition plan aimed at improving protein intake without exacerbating fluid retention. The patient is encouraged to incorporate high-protein, low-sodium foods into his diet and to monitor his caloric intake to combat fatigue. The nurse also provides additional education on recognizing signs of nutritional deficiencies and emphasizes the importance of regular follow-up appointments to track progress. By addressing these aspects, the team aims to enhance the patient's quality of life and minimize the risk of further complications from alcoholic cirrhosis.