cirrhosis - Nursing Case Study

Pathophysiology

• Primary mechanism: Chronic liver injury leads to repeated damage and healing, causing scar tissue (fibrosis) to replace healthy liver cells. This scar tissue disrupts normal liver architecture and function.

• Secondary mechanism: As fibrosis progresses, blood flow through the liver becomes obstructed, leading to increased pressure in the portal vein (portal hypertension). This affects blood filtering and nutrient processing.

• Key complication: Portal hypertension can cause fluid accumulation in the abdomen (ascites) and increase the risk of life-threatening complications like variceal bleeding due to swollen veins in the esophagus.

Patient Profile

Demographics:

45-year-old female, office manager

History:

• Key past medical history: Diagnosed with early-stage cirrhosis secondary to non-alcoholic fatty liver disease

• Current medications: Ursodeoxycholic acid, multivitamin

• Allergies: None

Current Presentation:

• Chief complaint: Routine follow-up for early-stage cirrhosis

• Key symptoms: Occasional fatigue, mild abdominal discomfort

• Vital signs: Blood pressure 118/76 mmHg, heart rate 78 bpm, respiratory rate 16 breaths per minute, temperature 98.6°F, oxygen saturation 98% on room air

Section 1

During the routine follow-up appointment, the nurse conducts an initial assessment of the patient. Upon examination, the patient reports experiencing occasional fatigue and mild abdominal discomfort, which she describes as a dull ache that occasionally intensifies after meals. The nurse notes that the patient appears well-nourished and in no acute distress. Her vital signs remain stable with a blood pressure of 118/76 mmHg, heart rate of 78 bpm, respiratory rate of 16 breaths per minute, and an oxygen saturation of 98% on room air. Her weight is stable compared to previous visits, and the BMI indicates she is within a healthy range.

The nurse performs a focused abdominal assessment, noting mild tenderness in the right upper quadrant upon palpation, but no significant hepatomegaly or spleen enlargement is detected. There is slight abdominal distension noted, but no signs of fluid wave or shifting dullness, which suggests that ascites, if present, is minimal and not clinically significant at this stage. Skin inspection reveals no jaundice or spider angiomas, and neurological assessment shows no signs of hepatic encephalopathy. The patient confirms adherence to her prescribed medication regimen, including ursodeoxycholic acid and a multivitamin, and reports no side effects.

The nurse reviews recent laboratory results, which indicate mildly elevated liver enzymes (ALT and AST), consistent with her diagnosis of early-stage cirrhosis. Bilirubin levels remain within the normal range, and albumin levels are slightly below normal, reflecting the liver's impaired synthetic function. The patient's INR is at the upper limit of normal, which may suggest early coagulopathy. These findings reinforce the importance of regular monitoring and lifestyle modifications, such as maintaining a balanced diet and avoiding alcohol, to slow disease progression. The nurse plans to discuss these results with the patient, emphasizing the importance of ongoing surveillance and adherence to treatment to manage her condition effectively.

Section 2

The nurse decides to focus on the patient's response to interventions, as maintaining her current health status is critical in managing early-stage cirrhosis. During the follow-up discussion, the nurse emphasizes the importance of adhering to dietary recommendations, such as a low-sodium diet to help manage fluid retention and a balanced intake of proteins to support liver function without overburdening the organ. The patient expresses a good understanding of these recommendations and shares that she has been meal planning with these guidelines in mind.

The patient reports that since implementing these dietary changes, she has noticed an improvement in her energy levels and a reduction in the frequency of abdominal discomfort. She attributes this to better meal timing and composition. The nurse reinforces the benefits of these lifestyle modifications and highlights the significance of avoiding alcohol entirely, given its potential to exacerbate liver damage. To support the patient's proactive approach, the nurse provides educational materials on nutrition and suggests regular follow-ups with a dietitian to refine her dietary plan further.

To ensure comprehensive care, the nurse arranges for the patient to undergo repeat laboratory testing in three months to monitor any changes in liver function and adjust the treatment plan accordingly. As the patient leaves the clinic, she expresses confidence in managing her condition and appreciation for the support and resources provided. The nurse notes this positive outlook in the patient's record, planning to continue building upon these health-promoting strategies in future visits to maintain stability in her cirrhotic condition.

Section 3

Three months later, the patient returns to the clinic for her scheduled follow-up appointment. During the initial assessment, the nurse notes that her vital signs are within normal limits: blood pressure is 120/78 mmHg, heart rate is 72 beats per minute, respiratory rate is 16 breaths per minute, and temperature is 98.6°F. The patient reports feeling generally well, with continued improvement in her energy levels and no significant abdominal discomfort. She mentions that she has been diligent with her low-sodium diet and has completely abstained from alcohol.

The results of the repeat laboratory tests are encouraging. Her liver function tests show a slight improvement: AST is 48 U/L (previously 52 U/L), ALT is 50 U/L (previously 55 U/L), and her albumin level is stable at 3.8 g/dL. Her bilirubin level remains slightly elevated at 1.4 mg/dL, but there has been no further increase. The nurse notes the absence of any new signs of liver decompensation, such as jaundice or ascites, and confirms that her weight has remained stable, indicating effective management of fluid retention.

These positive clinical indicators reflect the patient's adherence to her management plan and the effectiveness of the interventions. The nurse commends her efforts and encourages continued adherence to dietary recommendations and lifestyle modifications. Recognizing the importance of ongoing support, the nurse suggests scheduling another follow-up appointment in three months and recommends continuing regular consultations with the dietitian. The nurse also provides additional educational materials on managing early-stage cirrhosis and discusses the importance of recognizing any new symptoms promptly. The patient leaves the clinic feeling empowered and supported, determined to maintain her current health trajectory.

Section 4

Three months later, the patient returns for her follow-up appointment, appearing more vibrant and reporting a further increase in her energy levels. During the initial assessment, her vital signs remain stable: blood pressure is 118/76 mmHg, heart rate is 70 beats per minute, respiratory rate is 16 breaths per minute, and temperature is 98.4°F. She expresses satisfaction with her current health status and mentions that she has been able to engage in more physical activities, such as daily walks, without experiencing fatigue. The nurse observes no signs of jaundice, and her abdomen remains soft and non-tender, without any signs of ascites.

The new laboratory results show continued improvement in her liver function tests: her AST has decreased to 45 U/L, and ALT is now at 47 U/L. Her albumin level remains stable at 3.9 g/dL, and her bilirubin has slightly decreased to 1.3 mg/dL. These results suggest that the patient's diligent adherence to her management plan is yielding positive outcomes. The nurse takes this opportunity to reinforce the importance of maintaining her low-sodium diet and abstaining from alcohol, as these factors are critical in managing her early-stage cirrhosis effectively.

Given the positive trends, the nurse discusses the potential for gradually incorporating additional physical activities, emphasizing the importance of pacing and listening to her body's signals to avoid overexertion. Additionally, the nurse advises the patient on monitoring for any subtle changes in her condition, such as increased fatigue or abdominal discomfort, which should be reported promptly. The patient is encouraged to continue her regular follow-ups with the healthcare team, including the dietitian, to ensure comprehensive support in managing her condition. Feeling motivated and supported, the patient leaves the clinic with a renewed commitment to her health plan, optimistic about the future.

Section 5

Three months after the last follow-up, the patient returns for another routine check-up. During the initial assessment, the nurse notes that the patient's vital signs are stable: blood pressure is 116/74 mmHg, heart rate is 72 beats per minute, respiratory rate is 17 breaths per minute, and temperature is 98.2°F. The patient reports feeling well overall, though she mentions experiencing occasional, mild right upper quadrant discomfort, particularly after meals. Despite this, she continues to engage in her daily walks and has started attending a gentle yoga class, which she finds beneficial for her stress levels and overall well-being.

New laboratory results reveal that her liver function tests remain largely stable, with a slight increase in AST to 50 U/L and ALT to 52 U/L, which are still within a manageable range. Her albumin level is consistent at 3.9 g/dL, and bilirubin remains at 1.3 mg/dL. These values suggest the patient's liver function is still relatively stable, but the slight increase in liver enzymes prompts the healthcare team to consider potential dietary or lifestyle factors that may be contributing. The nurse reviews the patient's diet and medication adherence, ensuring that she continues to avoid alcohol and maintains her low-sodium intake.

In light of these findings, the nurse discusses the importance of monitoring her dietary habits closely and encourages the patient to keep a food diary to identify any possible triggers for her discomfort. The nurse also reinforces the significance of continuing her physical activities at a comfortable pace and listening to her body's signals. The patient is reminded to report any persistent or worsening symptoms, such as increased abdominal pain or changes in her stool, promptly. With a clear plan in place and reassurance from her healthcare team, the patient leaves the clinic feeling empowered to continue managing her condition actively, looking forward to her next follow-up appointment.