GI Bleed - Nursing Case Study
Pathophysiology
• Primary mechanism: Mucosal erosion or ulceration, often due to peptic ulcers or gastritis, leads to the loss of protective mucosal lining, exposing blood vessels to gastric acid and resulting in hemorrhage.
• Secondary mechanism: Variceal bleeding from portal hypertension, commonly due to cirrhosis, causes increased pressure in the portal venous system, leading to the rupture of esophageal or gastric varices.
• Key complication: Significant blood loss can lead to hypovolemic shock, where decreased blood volume results in inadequate organ perfusion and potential multi-organ failure if not promptly managed.
Patient Profile
Demographics:
56-year-old male, construction worker
History:
• Key past medical history: Hypertension, Peptic Ulcer Disease
• Current medications: Lisinopril, Omeprazole, Aspirin
• Allergies: Penicillin
Current Presentation:
• Chief complaint: Bloody stools and dizziness
• Key symptoms: Hematochezia, fatigue, abdominal pain, lightheadedness
• Vital signs: Blood pressure 98/60 mmHg, heart rate 110 bpm, respiratory rate 22 breaths per minute, temperature 99.1°F
Section 1
As the healthcare team delves deeper into the patient's condition, further initial assessment findings reveal crucial insights. The physical examination corroborates the patient's complaints: he appears pale with cool, clammy skin, suggestive of compromised peripheral perfusion. Abdomen is tender to palpation, especially in the epigastric region, without rebound tenderness or guarding, which may indicate active peptic ulceration rather than perforation. Orthostatic hypotension is evident, with a drop in blood pressure to 88/56 mmHg upon standing, and his heart rate increases to 120 bpm, pointing towards significant intravascular volume depletion. Bloodwork reveals a hemoglobin level of 8.5 g/dL, hematocrit at 25%, and a slightly elevated blood urea nitrogen (BUN) to creatinine ratio, typical of upper gastrointestinal bleeding.
These findings prompt the medical team to prioritize restoring hemodynamic stability while investigating the bleeding source. The patient receives intravenous fluids, and a proton pump inhibitor is administered intravenously to reduce gastric acid secretion. Given the potential for peptic ulcer bleeding, an urgent esophagogastroduodenoscopy (EGD) is planned to visualize and manage any active bleeding sites. In parallel, the team considers the potential for variceal bleeding, given the patient's hypotension and tachycardia, although there is no known history of liver disease.
These interim interventions aim to stabilize the patient while diagnostic efforts are underway. The clinical scenario underscores the importance of promptly addressing hypovolemia to prevent progression to hypovolemic shock and organ dysfunction. The team must remain vigilant for signs of new complications, such as worsening anemia or changes in mental status, which would necessitate immediate reassessment and escalation of care. This phase of the patient's journey will set the stage for determining the bleeding etiology and tailoring further treatment strategies.
Section 2
As the healthcare team continues to monitor the patient closely, a change in his status prompts immediate attention. Despite initial interventions, the patient's condition begins to deteriorate. His vital signs reveal a concerning trend: the heart rate has climbed to 130 bpm, and blood pressure has further dropped to 82/50 mmHg. His skin remains pale and clammy, and he is now intermittently confused, indicating potential cerebral hypoperfusion. These signs are alarming for evolving hypovolemic shock, necessitating rapid reassessment and intervention.
Laboratory results return, showing a further drop in hemoglobin to 7.8 g/dL and hematocrit to 23%, confirming ongoing blood loss. The slightly elevated lactic acid level suggests tissue hypoxia, a marker of worsening perfusion. Additionally, the patient has developed mild metabolic acidosis, with an arterial blood gas showing a pH of 7.32 and bicarbonate of 19 mEq/L, secondary to poor tissue perfusion and oxygenation. The medical team decides to escalate care by transfusing packed red blood cells to address the significant anemia and improve oxygen delivery to tissues.
Given the patient's rapid decline and inadequate response to fluid resuscitation, the team accelerates plans for esophagogastroduodenoscopy (EGD) to urgently identify and potentially treat the bleeding source. The nursing team remains vigilant, continuously monitoring for any signs of respiratory compromise or further hemodynamic instability. As the patient is prepped for the procedure, the team discusses the possibility of additional complications, such as aspiration or worsening hemodynamic status during sedation, and prepares to manage these risks. The unfolding situation emphasizes the critical need for timely intervention and coordinated care to stabilize the patient and prevent further deterioration.
Section 3
As the healthcare team prepares the patient for esophagogastroduodenoscopy (EGD), they notice a change in his respiratory status, signaling a new complication that demands urgent attention. The patient’s respiratory rate has increased to 28 breaths per minute, and his oxygen saturation has dropped to 88% on room air, indicating the potential for respiratory compromise. Auscultation of the lungs reveals diminished breath sounds at the bases with scattered crackles, suggesting fluid overload or early signs of pulmonary edema, potentially due to aggressive fluid resuscitation.
Recognizing the critical need to stabilize the patient's respiratory function, the team initiates supplemental oxygen via a non-rebreather mask, improving his oxygen saturation to 94%. However, the patient's increased work of breathing and the potential risk of aspiration during the upcoming EGD procedure necessitate further intervention. The team considers the potential benefits and risks of non-invasive ventilation or intubation, given the patient's hemodynamic instability and ongoing risk of aspiration due to his GI bleed and recent confusion.
These developments prompt the team to perform a repeat chest X-ray, which reveals bilateral infiltrates, consistent with fluid overload and possible aspiration pneumonitis. The nursing and medical teams collaborate to adjust the patient's fluid management plan, carefully balancing the need for volume resuscitation with the risk of exacerbating pulmonary complications. This situation highlights the importance of dynamic clinical reasoning and interdisciplinary coordination to adapt the care plan in response to the evolving clinical picture, ensuring the patient's respiratory and hemodynamic stability as they proceed with the EGD to address the source of bleeding.
Section 4
As the healthcare team continues to manage the patient’s condition, they closely monitor his response to the interventions. Despite the initial improvement in oxygen saturation with supplemental oxygen, the patient's respiratory status remains precarious. His respiratory rate, though slightly reduced, still hovers around 26 breaths per minute, indicating ongoing respiratory distress. The patient appears increasingly lethargic, with diminished responsiveness, which raises concerns about his neurological status possibly being affected by hypoxia or the underlying GI bleed.
New diagnostic results from arterial blood gas (ABG) analysis reveal a pH of 7.32, PaCO2 of 50 mmHg, and PaO2 of 58 mmHg on the non-rebreather mask, indicating respiratory acidosis with hypoxemic features. These findings suggest that the patient's respiratory compromise is worsening despite initial measures, likely due to fluid overload and potential aspiration contributing to impaired gas exchange. Additionally, laboratory tests show a hemoglobin level of 7.4 g/dL, reflecting significant blood loss and necessitating further consideration of blood transfusion to stabilize his hemodynamic status.
Recognizing the urgency, the healthcare team decides to proceed with intubation to secure the airway and provide controlled ventilation, reducing the risk of aspiration during the EGD procedure. This decision is reinforced by the patient's continued hemodynamic instability, as indicated by a blood pressure of 90/60 mmHg and a heart rate of 118 beats per minute. The interdisciplinary team prepares for the procedure, emphasizing the importance of meticulous coordination and dynamic clinical reasoning to navigate these complex challenges. The focus remains on maintaining the patient's stability while addressing the source of the GI bleed, which remains a critical step in his overall recovery.
Section 5
As the healthcare team proceeds with the intubation, the procedure is successfully completed without complications, and the patient is placed on mechanical ventilation. Initial ventilator settings are adjusted to support adequate oxygenation and ventilation, aiming to correct the respiratory acidosis and improve the patient's oxygenation status. Post-intubation, a follow-up arterial blood gas (ABG) analysis is conducted, revealing a pH of 7.38, PaCO2 of 45 mmHg, and PaO2 of 80 mmHg. These results indicate a partial correction of the acidosis and an improvement in oxygenation, suggesting that the intervention is having a positive effect on the patient's respiratory status.
However, the patient's hemodynamic status remains a concern. Despite the administration of fluid resuscitation and blood transfusion, his blood pressure remains at 92/58 mmHg, with a heart rate of 112 beats per minute. The repeated hemoglobin level shows a slight improvement to 8.1 g/dL, but the persistent hypotension suggests ongoing bleeding or inadequate volume replacement. The team considers the possibility of a more significant or undetected source of blood loss, prompting a decision to expedite the esophagogastroduodenoscopy (EGD) to identify and manage the bleeding source.
While preparing for the EGD, the patient's urinary output is closely monitored, showing a decrease to 20 mL/hour, raising concerns of renal hypoperfusion. The interdisciplinary team discusses the need for further imaging, such as a CT scan of the abdomen, to rule out other potential complications like perforation or extensive bleeding that may not be immediately apparent. The team remains vigilant, balancing the urgency of the situation with the need for a comprehensive assessment to guide their next steps effectively.