post op knee replacement surgery care plan - Nursing Case Study

Pathophysiology

• Primary mechanism: Inflammation - Post knee replacement, surgical trauma initiates the inflammatory process, leading to increased vascular permeability and inflammatory mediator release. This can cause swelling and pain, impacting mobility and recovery.

• Secondary mechanism: Thromboembolism - Venous stasis and endothelial damage during surgery elevate the risk of deep vein thrombosis (DVT). Reduced mobility post-operatively further contributes to thrombus formation, necessitating anticoagulation and mobilization strategies.

• Key complication: Infection - Surgical site infection can occur due to breached skin barriers and immune response alterations. Vigilant aseptic techniques and monitoring are essential to prevent infections that can compromise prosthesis function and patient recovery.

Patient Profile

Demographics:

65-year-old female, retired school teacher

History:

• Key past medical history: Osteoarthritis, hypertension, type 2 diabetes

• Current medications: Metformin, Lisinopril, Acetaminophen

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Increasing pain and swelling in the operated knee

• Key symptoms: Redness and warmth around the surgical site, difficulty bearing weight, fatigue

• Vital signs: Temperature 100.4°F, Blood pressure 150/90 mmHg, Heart rate 92 bpm, Respiratory rate 20 breaths per minute

Section 1

As the clinical team continues to monitor the patient, the initial assessment reveals several concerning findings. The surgical site on the right knee exhibits increased erythema and warmth, extending slightly beyond the incision line. The patient's pain, described as throbbing and persistent, is rated as 8 out of 10 on the pain scale, despite regular doses of acetaminophen. Furthermore, the patient reports an increase in fatigue and a sense of generalized malaise. On physical examination, there is noted difficulty with active range of motion, and the patient is increasingly reluctant to bear weight on the affected leg, requiring more assistance for ambulation than anticipated at this post-operative stage.

Laboratory results return with elevated white blood cell count at 14,500/mm³, indicating a possible infectious process, paired with an elevated C-reactive protein level of 8.2 mg/L, suggesting systemic inflammation. The patient's blood glucose levels have also been erratic, with recent recordings showing hyperglycemia, which could compromise her healing process. These findings raise suspicion for a developing surgical site infection, necessitating further investigation and possible modification of her current care plan.

Given these developments, the healthcare team decides to obtain a wound culture and initiate empirical broad-spectrum antibiotics due to the high suspicion of infection, while awaiting culture results for targeted therapy. The patient's anticoagulation therapy is carefully evaluated to balance the risk of thromboembolism against the potential for bleeding in the context of infection and inflammation. These steps are crucial in preventing further complications, such as prosthetic joint infection, which could severely hinder her recovery trajectory. The team also emphasizes the importance of maintaining strict glycemic control and considers involving a multidisciplinary approach, including infectious disease and orthopedic specialists, to optimize her care and recovery.

Section 2

As the healthcare team continues to monitor the patient, they note a change in her status that warrants immediate attention. Despite the initiation of broad-spectrum antibiotics, the patient's condition appears to be deteriorating. Her vital signs reveal a mild fever of 38.2°C (100.8°F), tachycardia with a heart rate of 112 beats per minute, and a slight hypotension with blood pressure readings averaging 100/60 mmHg. These signs suggest a systemic response to the infection, potentially leading to early sepsis if not addressed promptly.

The team observes that the patient's pain has become increasingly difficult to manage, with her rating it now as 9 out of 10. The erythema around the knee has expanded, and purulent drainage is noted at the incision site, indicating a likely bacterial infection. The wound culture results return, identifying methicillin-resistant Staphylococcus aureus (MRSA) as the causative organism. In response, the healthcare team adjusts the antibiotic regimen to include vancomycin, targeting this resistant pathogen more effectively.

In terms of clinical reasoning, the team must assess the impact of the infection on the patient's overall recovery, considering her elevated risk for prosthetic joint complications. They also need to evaluate her anticoagulation therapy, given the increased risk of bleeding associated with infection and inflammation. The patient's erratic blood glucose levels further complicate her recovery, necessitating a thorough review of her diabetic management plan to ensure optimal wound healing. This situation underscores the importance of a multidisciplinary approach, with infectious disease and orthopedic specialists playing pivotal roles in refining her treatment strategy, ultimately aiming to stabilize her condition and prevent further complications.

Section 3

As the healthcare team closely monitors the patient, they note that despite the adjustment in antibiotic therapy to include vancomycin, the patient's condition continues to show signs of deterioration. Her vital signs remain concerning with a persistent fever, now climbing to 38.5°C (101.3°F), and her tachycardia has intensified, with a heart rate of 118 beats per minute. Blood pressure readings have further declined, averaging 95/58 mmHg, indicating a potential progression towards septic shock. Clinically, the patient appears increasingly lethargic, and her extremities are cool to the touch, suggesting compromised perfusion.

Laboratory results provide additional cause for concern. The patient's white blood cell count has markedly increased to 16,500/mm³, indicating a heightened inflammatory response. Her blood glucose levels are erratic, with episodes of hyperglycemia reaching 240 mg/dL, likely exacerbated by the stress of infection and inflammation. A recent blood culture reveals bacteremia, confirming that the MRSA infection has disseminated into the bloodstream. This finding necessitates an urgent reassessment of her treatment plan, emphasizing the need for aggressive fluid resuscitation and potentially the initiation of vasopressors to support hemodynamic stability.

The team recognizes the critical need for a coordinated multidisciplinary approach to mitigate the risk of further complications. Infectious disease specialists are consulted to refine antibiotic therapy, while the diabetic management team optimizes insulin protocols to control blood sugar levels effectively. Orthopedic surgeons evaluate the integrity of the prosthetic joint, considering the potential need for surgical intervention if the infection does not respond to medical management. The complex interplay of these factors highlights the delicate balance required in managing such a high-risk postoperative patient, with the focus shifting towards preventing irreversible complications and promoting recovery.

Section 4

As the healthcare team continues to manage the patient’s deteriorating condition, they prioritize aggressive fluid resuscitation to combat her hypotension and improve tissue perfusion. However, despite administering multiple liters of isotonic saline intravenously, the patient's blood pressure remains low, hovering around 90/55 mmHg. Her heart rate has climbed further to 124 beats per minute, and she remains febrile with a temperature of 38.8°C (101.8°F). Moreover, the patient’s respiratory rate has increased to 24 breaths per minute, and she displays signs of respiratory distress, including shallow, labored breathing and the use of accessory muscles. These changes prompt the team to initiate norepinephrine infusion, a vasopressor, to stabilize her hemodynamics and prevent progression to septic shock.

The situation becomes more complex when new laboratory results reveal a decreased hemoglobin level of 8.2 g/dL, a drop from previous measurements, suggesting potential hemolysis or bleeding. Concurrently, an arterial blood gas analysis indicates metabolic acidosis, with a pH of 7.30 and bicarbonate level of 18 mmol/L, likely resulting from a combination of poor tissue perfusion and lactic acid accumulation. These findings necessitate a reassessment of her oxygenation status and potential need for mechanical ventilation support. The healthcare team collaborates to adjust her care plan, acknowledging the need to address the multifactorial causes of her current state, including optimizing fluid balance, ensuring adequate oxygen delivery, and closely monitoring for any signs of bleeding or further hematological compromise.

In light of these developments, the orthopedic team re-evaluates the knee joint prosthesis for signs of loosening or infection spread, using imaging modalities such as an X-ray or MRI to assess the situation accurately. Additionally, they consider the possibility of surgical debridement if the infection proves unresponsive to antibiotic therapy alone. The patient's family is updated on the critical nature of her condition, informed of the ongoing interventions, and involved in discussions about the potential next steps, including surgical options. This comprehensive approach underscores the importance of timely, coordinated care and continuous reassessment to navigate the complexities of postoperative complications in this vulnerable patient.

Section 5

As the healthcare team continues to monitor the patient's response to the initiated norepinephrine infusion and aggressive fluid resuscitation, they observe a modest improvement in her blood pressure, which stabilizes at 100/60 mmHg. However, her heart rate remains elevated at 120 beats per minute, and her fever persists despite antipyretic administration, indicating a possible ongoing infectious process. The patient’s respiratory distress becomes more pronounced, with an increased respiratory rate of 28 breaths per minute and oxygen saturation dropping to 88% on room air, prompting the team to escalate oxygen therapy and prepare for potential intubation if her condition does not improve.

In response to these concerning signs, further diagnostic tests are conducted to identify underlying causes and guide treatment adjustments. A repeat complete blood count reveals a continued decline in hemoglobin, now at 7.8 g/dL, and a significant leukocytosis with a white blood cell count of 18,000/mm³, supporting the suspicion of an infectious or inflammatory process. Cultures obtained from blood and joint aspirate are pending, but the clinical suspicion of septicemia or prosthetic joint infection intensifies. In light of these findings, broad-spectrum antibiotics are initiated empirically, and discussions with the infectious disease team are prioritized to tailor antimicrobial therapy once culture results are available.

As the patient’s condition remains precarious, the orthopedic and critical care teams collaborate closely to reassess her overall status and devise a comprehensive management plan. Given the risks associated with ongoing infection and hematological instability, they deliberate over the potential benefits and risks of surgical intervention, such as debridement or revision arthroplasty, should localized infection be confirmed. The critical nature of her condition is communicated empathetically to her family, ensuring they are aware of the gravity of the situation and the rationale behind each clinical decision. This collaborative, multidisciplinary approach aims to address the root causes of her deterioration while providing the best chance for recovery through timely, evidence-based interventions.