Anxiety - Nursing Case Study

Pathophysiology

• Primary mechanism: Dysregulation of neurotransmitters such as serotonin, norepinephrine, and gamma-aminobutyric acid (GABA) leads to imbalances that heighten the stress response, causing excessive anxiety symptoms.

• Secondary mechanism: Overactivity of the hypothalamic-pituitary-adrenal (HPA) axis results in increased cortisol production, which exacerbates the body's stress response and perpetuates anxiety.

• Key complication: Chronic anxiety can lead to physical health issues like hypertension and cardiovascular disease due to sustained stress hormone levels, highlighting the importance of early identification and management.

Patient Profile

Demographics:

32-year-old female, marketing manager

History:

• Key past medical history: Generalized anxiety disorder diagnosed 5 years ago, occasional tension headaches

• Current medications: Sertraline 50 mg daily, occasional use of lorazepam 0.5 mg as needed for acute anxiety episodes

• Allergies: Penicillin (rash)

Current Presentation:

• Chief complaint: Increasing episodes of anxiety and panic attacks over the past month

• Key symptoms: Restlessness, palpitations, shortness of breath, difficulty concentrating, insomnia, frequent tension headaches, gastrointestinal discomfort

• Vital signs: Blood pressure 142/88 mmHg, heart rate 102 bpm, respiratory rate 22 breaths per minute, temperature 98.6°F, oxygen saturation 97% on room air

Section 1

New Diagnostic Results:

Following the patient's presentation with increasing anxiety symptoms and physiological manifestations, additional diagnostic evaluations were conducted to assess potential complications and rule out other underlying conditions. Comprehensive blood work revealed elevated cortisol levels, consistent with an overactive hypothalamic-pituitary-adrenal (HPA) axis, supporting the hypothesis of heightened stress response contributing to her anxiety. Thyroid function tests indicated slightly elevated thyroid-stimulating hormone (TSH) levels, suggesting the possibility of subclinical hypothyroidism, which can exacerbate anxiety symptoms. Additionally, a complete blood count and basic metabolic panel were unremarkable, with no indications of anemia or electrolyte imbalances that might contribute to her symptoms.

An electrocardiogram (ECG) was performed to evaluate the cardiovascular effects of chronic anxiety, given her elevated blood pressure and heart rate. The ECG showed sinus tachycardia but no ischemic changes, indicating that while the heart is under stress, there is no immediate cardiac damage. However, sustained elevated blood pressure and heart rate due to chronic anxiety could predispose her to long-term cardiovascular issues if not managed effectively. These findings emphasize the need for a holistic approach in managing her anxiety, including potential adjustments to her medication regimen, lifestyle modifications, and possibly initiating cognitive-behavioral therapy (CBT) to address both psychological and physiological components of her anxiety disorder.

These diagnostic results guide the healthcare team in refining the treatment plan, focusing on stabilizing her anxiety symptoms and addressing the physiological contributors identified. The potential for subclinical hypothyroidism as a contributing factor may warrant further endocrinological evaluation and consideration of appropriate interventions. With these insights, the next steps will involve close monitoring of her response to any therapeutic adjustments and regular follow-up to mitigate the risk of progression to more severe health complications. The interconnectedness of her symptoms and diagnostic findings presents an opportunity for clinical reasoning to explore multifaceted treatment strategies.

Section 2

Change in Patient Status:

Two weeks after the initial intervention adjustments, the patient returns for a follow-up appointment. During this visit, she reports mixed feelings about the changes in her treatment plan. While she experiences some improvement in her anxiety levels, manifesting as fewer panic attacks and a slightly improved ability to manage daily stressors, she also reports new symptoms that have arisen. She mentions persistent fatigue and difficulty concentrating, which are affecting her work performance and daily activities. These symptoms raise concerns about the potential exacerbation of her subclinical hypothyroidism or side effects from her anxiety medications.

A thorough physical assessment reveals that her blood pressure remains slightly elevated at 142/88 mmHg, and her heart rate is consistently high, averaging around 98 beats per minute. Although her anxiety symptoms have decreased, the sustained tachycardia and hypertension suggest that her physiological stress response is still active. The healthcare team decides to conduct further thyroid function tests to assess any changes in her TSH levels, as well as consider a possible adjustment to her medication regimen to better balance her anxiety management with these new symptoms.

The clinical team recognizes the need to address these emerging complications through a more integrated approach. This includes potentially collaborating with an endocrinologist to explore the implications of her thyroid function on her current symptoms and refining her anxiety treatment plan to minimize side effects. These steps highlight the importance of continuous evaluation and adjustment in her care, ensuring all contributing factors to her condition are adequately managed. The interconnectedness of her mental health and physiological state requires ongoing attention to prevent escalation of symptoms and safeguard her overall well-being.

Section 3

The new diagnostic results are in, and they provide crucial insights into the patient's condition. The thyroid function tests reveal a slight increase in her TSH levels, now at 5.2 mIU/L, which suggests a mild progression of her subclinical hypothyroidism. This finding could be contributing to her fatigue and difficulty concentrating, as her thyroid hormones might not be adequately supporting her metabolic needs. Meanwhile, her complete blood count and metabolic panel are within normal limits, ruling out anemia or significant electrolyte imbalances as causes for her symptoms.

Given the interplay between her thyroid function and anxiety management, the healthcare team decides to adjust her treatment plan. They initiate a low-dose levothyroxine therapy to address the subclinical hypothyroidism, aiming to stabilize her TSH levels and alleviate her fatigue and cognitive difficulties. Concurrently, the team considers modifying her anxiety medication to reduce its potential contribution to her elevated heart rate and blood pressure. They plan to gradually taper her current medication while introducing an alternative with a lower side effect profile, such as a selective serotonin reuptake inhibitor (SSRI) that may offer better balance in managing her anxiety without exacerbating her physiological stress response.

These revised interventions are designed with careful consideration of the interconnected nature of her symptoms. The team schedules regular follow-ups to monitor her response to the new regimen, emphasizing the need for patient engagement and feedback to fine-tune her care. The plan also includes lifestyle recommendations, such as stress reduction techniques and dietary adjustments, to support her overall health and well-being. Through this integrated approach, the objective is to achieve a more harmonious balance between her mental and physical health, reducing the risk of further complications and enhancing her quality of life.

Section 4

Two weeks after initiating the adjusted treatment plan, the patient returns for a follow-up visit. During the initial assessment, the nurse notes several positive changes. The patient reports a noticeable improvement in her energy levels and reduced fatigue, which she attributes to the low-dose levothyroxine therapy. Her concentration and cognitive function also seem enhanced, allowing her to manage daily tasks more efficiently. Her vital signs show a heart rate of 78 beats per minute and a blood pressure reading of 118/76 mmHg, indicating a significant decrease from previous elevated levels. These improvements suggest that the adjustments to her medication regimen are beginning to stabilize her physiological responses.

However, the patient also reports experiencing intermittent headaches and a mild increase in weight, which she finds concerning. The nurse considers the potential side effects of her new SSRI medication, as well as the natural adjustments in metabolic rate due to thyroid hormone supplementation. A review of her diet and lifestyle changes reveals adherence to recommended stress reduction techniques and dietary modifications, but these symptoms warrant further investigation. The healthcare team decides to conduct a more detailed assessment, including a review of her current SSRI dosage and its potential interactions with other medications.

In light of these observations, the healthcare team plans to monitor her symptoms closely, particularly the headaches and weight changes, to determine if further medication adjustments are necessary. They emphasize the importance of ongoing communication with the patient, encouraging her to maintain a symptom diary to track any fluctuations or new developments. This collaborative approach aims to refine her treatment plan, ensuring that both her thyroid function and anxiety levels are optimally managed, minimizing the risk of new complications as her care progresses.

Section 5

Two weeks after the follow-up visit, the patient presents again, this time with more pronounced symptoms that suggest a potential new complication. She reports that the intermittent headaches have become more frequent and intense, often accompanied by visual disturbances such as seeing spots or experiencing blurred vision. Additionally, she expresses concern over a continuous upward trend in her weight, despite adhering to her dietary plan. During the assessment, her vital signs reveal a heart rate of 85 beats per minute and a blood pressure of 130/82 mmHg. Although still within the normal range, these readings are higher than her previous visit. The nurse notes that the patient appears slightly anxious, and her skin feels warm to the touch.

Given these new developments, the healthcare team decides to conduct a series of diagnostic tests to explore the underlying causes of her symptoms. A comprehensive metabolic panel is ordered to assess her electrolyte balance, liver function, and glucose levels. Additionally, a complete blood count and a thyroid panel, including TSH, Free T4, and Free T3 levels, are requested to evaluate any changes in her thyroid function that might be contributing to her symptoms. An eye examination is also scheduled to investigate the visual disturbances further.

As they await the diagnostic results, the healthcare team discusses the potential need to adjust her SSRI dosage, suspecting that it might be contributing to her headaches and weight changes. They emphasize the importance of a multidisciplinary approach to her care, considering consultations with an endocrinologist and a neurologist if her symptoms persist. This careful monitoring and collaborative strategy aim to address her current health issues while preventing further complications, ensuring a holistic approach to her anxiety management and overall well-being.