alzheimer's - Nursing Case Study

Pathophysiology

• Primary mechanism: Accumulation of beta-amyloid plaques - These protein fragments clump together between nerve cells in the brain, disrupting cell function and communication, leading to memory loss and cognitive decline.

• Secondary mechanism: Formation of tau tangles - Abnormal tau proteins inside brain cells form twisted tangles, destabilizing the cell's transport system, causing cell death and further impairing brain function.

• Key complication: Neurodegeneration - As plaques and tangles spread, they cause widespread brain cell death, leading to shrinking of brain tissue and loss of essential functions, impacting daily living activities and independence.

Patient Profile

Demographics:

72-year-old female, retired school teacher

History:

• Key past medical history: Hypertension, hyperlipidemia

• Current medications: Lisinopril, Atorvastatin, Donepezil

• Allergies: None

Current Presentation:

• Chief complaint: Mild memory loss

• Key symptoms: Occasional forgetfulness, difficulty recalling recent events, slight confusion in unfamiliar environments

• Vital signs: Blood pressure 130/80 mmHg, Heart rate 72 bpm, Respiratory rate 16 breaths per minute, Temperature 98.6°F

Section 1

Initial Assessment Findings:

Upon conducting a comprehensive assessment of the patient, several key findings emerged that align with her early stage Alzheimer's diagnosis. The patient's Mini-Mental State Examination (MMSE) score was documented at 24 out of 30, indicating mild cognitive impairment. During the interview, the patient occasionally struggled to recall the names of familiar objects and required prompting to complete simple tasks, such as outlining her daily routine. Despite these challenges, she remains generally oriented to person, time, and place, and her ability to engage in conversation and express her thoughts coherently is largely intact.

The physical assessment revealed no acute distress, and her vital signs remain stable: blood pressure 130/80 mmHg, heart rate 72 bpm, respiratory rate 16 breaths per minute, and temperature 98.6°F. The patient's neurological exam highlighted slight difficulty with short-term memory tasks but no significant motor deficits or sensory impairments. Her gait is steady, and she demonstrates independence in basic activities of daily living, though she occasionally misplaces personal items and requires reminders for medication adherence.

These findings suggest that while the patient is experiencing mild cognitive decline, her condition is stable, and she retains the capacity for self-care with minimal support. The focus now will be to implement strategies to enhance her memory function and maintain her quality of life, such as establishing routines, using memory aids, and ensuring a safe and supportive home environment. Regular follow-up appointments will be crucial to monitor her cognitive status and adjust care plans as needed, ensuring she continues to manage her hypertension and hyperlipidemia effectively alongside her Alzheimer's treatment.

Section 2

Response to Interventions:

In the weeks following the initial assessment, the patient has been actively participating in a structured cognitive stimulation program designed to help maintain her mental function. This program includes daily activities such as puzzles, memory games, and routine planning exercises, which she performs with the assistance of her family members. Her family has also introduced simple memory aids, such as labeled drawers and a daily calendar placed in a visible location, to help her navigate daily tasks more independently.

The patient has shown a positive response to these interventions. During a follow-up visit, her Mini-Mental State Examination (MMSE) score improved slightly to 25 out of 30, demonstrating modest gains in her short-term memory and task completion. She reports feeling more confident in managing her daily activities, though she still occasionally needs reminders, especially with new or unfamiliar tasks. Her family members note that she appears more engaged and less frustrated with her memory lapses, which has improved her overall mood and interactions at home.

Additionally, regular monitoring of her hypertension and hyperlipidemia continues to show stable results. Her blood pressure averages 128/78 mmHg, and her cholesterol levels remain within the target range. The patient adheres to her medication regimen with the help of a pill organizer and scheduled reminders. These efforts ensure her physical health remains stable, allowing her to focus on cognitive health improvements. Future plans include exploring community support groups and considering the introduction of a part-time caregiver to provide additional support as needed, fostering both her independence and social engagement.

Section 3

New Complications:

As the patient continues her journey with early-stage Alzheimer's, a minor complication arises. During a routine visit, she reports experiencing occasional dizziness and mild headaches, particularly in the mornings. Her vital signs remain stable, with a blood pressure reading of 130/80 mmHg and a heart rate of 72 beats per minute. However, these new symptoms prompt a closer examination of her current medication regimen and lifestyle habits.

Upon further investigation, it is discovered that the patient has been slightly dehydrated, likely due to a reduced fluid intake over the past few weeks. This dehydration could be contributing to her dizziness and headaches. Additionally, her blood work reveals a mild electrolyte imbalance, with slightly elevated sodium levels at 146 mmol/L, suggesting inadequate hydration. Her primary care provider recommends increasing her daily fluid intake and monitoring her symptoms closely, while also ensuring her blood pressure is not fluctuating significantly.

In light of these findings, the patient and her family are educated on the importance of maintaining adequate hydration and are encouraged to implement strategies to remind her to drink fluids regularly, such as setting alarms or using a hydration app. The family is also advised to observe her for any changes in her symptoms or any new concerns, ensuring she stays on track with her cognitive and physical health management. With these adjustments, the team is optimistic that her symptoms will resolve, allowing her to continue benefiting from her cognitive stimulation program and maintain her current level of independence.

Section 4

Response to Interventions:

Following the implementation of the hydration strategy, the patient shows notable improvement in her symptoms. Her family diligently assists her by setting reminders for regular fluid intake, which the patient follows with enthusiasm. Within a week, her dizziness and morning headaches significantly decrease, allowing her to resume her daily activities with more ease and confidence. Her follow-up vitals are stable, with a blood pressure of 128/78 mmHg and a heart rate of 70 beats per minute. These stable readings suggest that her cardiovascular system is coping well with the increased hydration.

A repeat blood test reveals that her sodium levels have normalized to 142 mmol/L, indicating successful rehydration and resolution of the mild electrolyte imbalance. The nursing team continues to monitor her progress closely, reinforcing the importance of sustained hydration and adherence to her cognitive stimulation program. The family reports that the patient has been more alert and engaged during her cognitive exercises, suggesting an overall improvement in her well-being.

The healthcare team is pleased with the patient's positive response to the interventions and encourages her to maintain these habits to prevent future complications. They plan to continue regular follow-ups to ensure ongoing support and to address any new challenges that may arise. With her symptoms under control, the patient is able to maintain her independence and actively participate in her care, fostering a sense of empowerment and stability in her journey with early-stage Alzheimer's.

Section 5

New Complications:

As the patient continues her journey with early-stage Alzheimer's, the nursing team remains vigilant for any emerging complications. During a routine follow-up visit, the family reports that the patient has started exhibiting mild difficulty with verbal expression, occasionally struggling to find the right words during conversations. While these episodes are infrequent, they have caused some frustration for the patient, who is eager to maintain her communication skills. The nursing staff conducts a comprehensive assessment, noting that her Mini-Mental State Examination (MMSE) score has slightly declined from 26 to 24, indicating a minor progression in cognitive impairment.

In response to these new challenges, the healthcare team collaborates with a speech therapist to develop a tailored intervention plan aimed at enhancing the patient's language skills. The plan includes simple word-retrieval exercises, naming activities, and conversational practice, which are integrated into her daily routine in a manner that is enjoyable and engaging for the patient. The family is encouraged to participate in these exercises, reinforcing a supportive environment for communication improvement.

The team also decides to monitor the patient's nutritional status more closely, suspecting that her verbal difficulties may be linked to subtle changes in her overall health. A recent lab test shows that her glucose level is at 110 mg/dL, slightly above the normal range, which prompts a referral to a dietitian. The dietitian provides guidance on maintaining balanced blood sugar levels through diet, emphasizing the importance of regular meals and snacks rich in fiber and low in simple sugars. By addressing these new complications proactively, the healthcare team aims to support the patient's quality of life and slow the progression of her symptoms, ensuring she remains active and engaged in her care.