Acute Renal Injury in Adults - Nursing Case Study

Pathophysiology

• Primary mechanism: Decreased Blood Flow - Acute renal injury often starts with reduced blood flow to the kidneys, known as prerenal azotemia. This can be due to dehydration, heart failure, or other conditions that lower blood pressure, leading to insufficient oxygen and nutrients reaching kidney tissues.

• Secondary mechanism: Direct Kidney Damage - Conditions like toxins or infections can directly harm kidney cells. This intrinsic damage impairs the kidneys' ability to filter waste from the blood, causing waste buildup and fluid imbalance.

• Key complication: Fluid and Electrolyte Imbalance - As kidney function declines, the body struggles to maintain fluid and electrolyte balance, potentially leading to swelling, high blood potassium levels, and increased risk of heart complications.

Patient Profile

Demographics:

45-year-old male, office worker

History:

• Key past medical history: Hypertension, Hyperlipidemia

• Current medications: Lisinopril 10 mg daily, Atorvastatin 20 mg daily

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Decreased urine output

• Key symptoms: Mild fatigue, slight swelling in ankles

• Vital signs: Blood Pressure 128/82 mmHg, Heart Rate 76 bpm, Respiratory Rate 18 breaths/min, Temperature 98.6°F

Section 1

Initial Assessment Findings:

Upon admission, the nursing assessment reveals that the patient's decreased urine output has resulted in oliguria, producing less than 400 mL of urine in a 24-hour period. A physical examination confirms mild pitting edema in the ankles, consistent with fluid retention due to the kidneys' impaired ability to regulate fluid and electrolyte balance. The patient reports experiencing mild fatigue, which has gradually increased over the past week. His skin turgor and mucous membranes appear slightly dry, suggesting possible dehydration contributing to prerenal azotemia.

The nurse monitors the patient's vital signs closely, noting that the blood pressure remains stable at 128/82 mmHg, indicating that while there is no acute hypertensive crisis, the kidney's compromised function still poses a risk to maintaining blood pressure homeostasis. Heart rate and respiratory rate are within normal limits, at 76 bpm and 18 breaths/min respectively, suggesting the absence of immediate cardiac or respiratory distress. Temperature is normal at 98.6°F, ruling out fever as a current complicating factor.

The initial lab tests show elevated blood urea nitrogen (BUN) and creatinine levels, with a BUN of 32 mg/dL and creatinine of 2.1 mg/dL, confirming impaired renal function. The nurse recognizes the importance of monitoring these values to assess the progression of the renal injury. Electrolyte analysis reveals a potassium level at the upper limit of normal at 5.0 mEq/L, necessitating careful monitoring to prevent hyperkalemia. The nurse initiates a fluid management plan, ensuring adequate hydration to improve renal perfusion, and collaborates with the healthcare team to adjust medication doses as needed to support renal recovery.

Section 2

Response to Interventions:

After implementing the fluid management plan, the nursing team observes an improvement in the patient's urine output, with a gradual increase to 500 mL over the next 24 hours. This positive response suggests that the rehydration efforts are beginning to enhance renal perfusion and function. The patient's mild fatigue also shows slight improvement, indicating that the body is effectively utilizing the increased fluid intake. The nursing staff continues to monitor the patient's fluid balance closely, ensuring that intake and output are accurately recorded to prevent fluid overload, which could exacerbate the existing edema.

Subsequent lab results show a slight decrease in BUN and creatinine levels, with BUN at 28 mg/dL and creatinine at 1.9 mg/dL. These changes reflect a favorable response to the interventions, indicating a stabilization of renal function. The electrolyte panel reveals that the potassium level remains stable at 4.9 mEq/L, alleviating concerns about the potential development of hyperkalemia. The patient's blood pressure maintains a stable reading of 126/80 mmHg, confirming the effectiveness of the fluid management plan in supporting cardiovascular stability.

The nurse continues to educate the patient on the importance of adhering to the prescribed fluid regimen and medications. The nursing team also reinforces dietary recommendations that include a low-potassium diet, which is crucial in maintaining electrolyte balance as the kidneys recover. This ongoing education empowers the patient to actively participate in their care plan, which is essential for successful long-term management of renal health. The next steps involve reevaluating the patient's condition and adjusting the care plan as needed, ensuring consistent and individualized care.

Section 3

New Diagnostic Results:

As the care plan progresses, the healthcare team orders a follow-up renal ultrasound to assess any structural changes and further evaluate renal perfusion. The ultrasound reveals no significant abnormalities, indicating that the kidneys are not obstructed and there is no evidence of acute structural damage. This finding supports the initial assessment that the acute renal injury is likely due to reversible causes, such as dehydration or medication effects, rather than chronic or irreversible damage.

Simultaneously, a repeat urinalysis is performed, showing a reduction in proteinuria and the absence of any new casts or blood cells, which further supports the improving renal function. The patient's glomerular filtration rate (GFR) is recalculated, now at 56 mL/min/1.73 m², showing a slight but encouraging improvement from previous values. The nurse discusses these results with the patient, emphasizing the importance of continuing the current treatment plan, which includes maintaining adequate hydration and adhering to any medication adjustments prescribed by the healthcare provider.

These diagnostic results provide reassurance to both the patient and the healthcare team, reinforcing the effectiveness of the current interventions. The patient is encouraged to continue following dietary recommendations and to remain vigilant about fluid intake. Moving forward, the team plans to monitor the patient's renal function regularly, ensuring any further changes are promptly addressed to maintain the trajectory towards full recovery. The narrative will next explore any potential lifestyle adjustments or follow-ups needed as part of the patient's journey to better health.

Section 4

As the patient continues to receive care for acute renal injury, the healthcare team observes a positive response to the interventions. The patient's vital signs remain stable, with a blood pressure of 118/75 mmHg and a heart rate of 72 beats per minute. The patient reports feeling more energetic, with improved urination patterns and no further episodes of dizziness or fatigue. Lab tests indicate that blood urea nitrogen (BUN) and creatinine levels have decreased slightly, aligning with the improving glomerular filtration rate (GFR). Current BUN levels are at 24 mg/dL, and serum creatinine is 1.3 mg/dL, demonstrating a gradual return towards normal renal function.

The nurse conducts a focused assessment, noting that the patient’s skin turgor has improved, and mucous membranes appear moist, confirming adequate hydration. The patient is attentive and engaged during discussions about their health, which is an encouraging sign of recovery. The nurse reinforces the importance of ongoing adherence to fluid intake recommendations, highlighting that consistent daily hydration is crucial to prevent recurrence of dehydration-related renal stress. The patient is reminded to monitor their fluid intake, aiming for at least 2 liters per day, unless otherwise directed by healthcare providers.

In light of these positive trends, the healthcare team schedules a follow-up appointment in two weeks to reassess renal function and ensure continued improvement. The patient is advised to report any signs of fluid imbalance, such as swelling or unexpected weight gain, and to maintain open communication with the healthcare team. As the patient progresses, the focus shifts to reinforcing lifestyle changes that support renal health, such as adopting a balanced diet low in sodium and avoiding nephrotoxic medications unless prescribed. Through these efforts, the patient is on a clear path towards recovery, with a proactive plan in place to sustain renal health long-term.

Section 5

Two weeks later, during the follow-up appointment, the patient arrives at the clinic feeling optimistic about their recovery. Upon initial assessment, the nurse notes that the patient's vital signs remain stable, with a blood pressure of 120/78 mmHg and a heart rate of 74 beats per minute. The patient reports feeling generally well, with no episodes of dizziness or fatigue since the last visit. They mention adhering to the recommended fluid intake and dietary guidelines, which they believe have contributed positively to their recovery. The nurse observes that the patient's skin remains well-hydrated, and there is no evidence of edema, indicating effective fluid balance management.

The latest lab results show further improvement, with a blood urea nitrogen (BUN) level of 22 mg/dL and serum creatinine at 1.1 mg/dL. These values suggest a continuing trend towards normalization of renal function, reflecting the efficacy of the ongoing treatment plan. The glomerular filtration rate (GFR) has also increased, confirming enhanced kidney performance. The patient expresses relief at these encouraging results and is motivated to maintain the lifestyle changes that have supported their recovery.

Given the positive trajectory, the healthcare team decides to continue the current management plan, with an emphasis on patient education. The nurse reviews key points with the patient, such as the importance of maintaining a low-sodium diet and avoiding over-the-counter medications that could harm the kidneys. The patient is also reminded to monitor for any warning signs of renal stress, such as changes in urine output or swelling, and to report these promptly. With a clear understanding of the steps necessary to sustain renal health, the patient leaves the appointment feeling empowered and confident in their ability to manage their condition effectively.