Partial Thickness Burns - Nursing Case Study

Pathophysiology

• Primary mechanism: Partial thickness burns, also known as second-degree burns, involve damage to both the epidermis and the dermis. The injury leads to the disruption of skin integrity, causing the death of keratinocytes and exposure of dermal structures, which results in fluid loss and blister formation.

• Secondary mechanism: Inflammatory response is triggered as part of the body's natural healing process. This involves the release of cytokines and other mediators, leading to increased vascular permeability and edema, which further contributes to pain and swelling in the affected area.

• Key complication: Infection risk increases due to the loss of the protective skin barrier. The open blistered areas provide an entry point for pathogens, necessitating vigilant wound care to prevent complications such as cellulitis or systemic infections.

Patient Profile

Demographics:

35-year-old male, construction worker

History:

• Key past medical history: Hypertension, Type 2 Diabetes

• Current medications: Metformin, Lisinopril

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Severe pain and blistering on the right arm and shoulder

• Key symptoms: Redness, swelling, and blister formation on affected areas; fever; increasing pain despite pain medication

• Vital signs: Temperature 38.5°C (101.3°F), Heart rate 110 bpm, Blood pressure 140/90 mmHg, Respiratory rate 22 breaths per minute, Oxygen saturation 95% on room air

Section 1

New Complications:

As the nursing team continues to monitor the patient, they notice a change in the character of the blistered areas on the right arm and shoulder. The blisters have begun to rupture, and the surrounding skin appears increasingly erythematous with a spreading area of warmth and tenderness. These observations raise immediate concerns about a potential infection. The patient’s fever persists, and his pain levels remain elevated despite analgesic administration. A wound culture is promptly obtained to identify any underlying bacterial infection, and a complete blood count (CBC) is ordered to assess for signs of systemic infection.

The CBC results reveal leukocytosis, with a white blood cell count of 14,500/mm³ (normal range: 4,500-11,000/mm³), indicating a heightened immune response likely due to infection. The differential shows a left shift with increased neutrophils, further supporting this suspicion. The patient also exhibits an elevated C-reactive protein (CRP) level of 15 mg/L (normal range: <3 mg/L), suggesting significant inflammation or infection. These findings, combined with the clinical signs of spreading erythema and warmth around the burn site, suggest the development of cellulitis.

Prompt intervention is required to manage this complication effectively. The healthcare team initiates broad-spectrum intravenous antibiotics, considering the patient's penicillin allergy. Additionally, wound care protocols are adjusted to ensure the affected areas are kept clean and protected from further contamination. The team closely monitors the patient's vital signs, particularly looking for any signs of sepsis such as hypotension or tachypnea. These interventions aim to contain the infection and prevent further systemic involvement, setting the stage for re-evaluation and potentially adjusting treatment based on culture results. The nursing staff also reinforces the importance of glycemic control in this diabetic patient to aid in the healing process and minimize further complications.

Section 2

As the nursing staff continues to monitor the patient's response to the initiated broad-spectrum intravenous antibiotics and adjusted wound care protocols, they observe several changes in the patient’s status that warrant further attention. Over the next 48 hours, the patient’s fever begins to subside slightly, now fluctuating between 100.4°F and 101.2°F, suggesting a partial response to the antibiotic therapy. However, the erythematous area on the right arm and shoulder does not exhibit significant improvement, and the patient continues to report a high level of pain at the burn site. The patient’s vital signs reveal new developments: his heart rate remains elevated, consistently measuring between 105-110 bpm, and there is a slight drop in blood pressure to 98/60 mmHg, raising concerns about possible early sepsis or inadequate perfusion.

Additionally, the results of the wound culture return and indicate the presence of methicillin-resistant Staphylococcus aureus (MRSA), a finding that necessitates a change in the antibiotic regimen. The healthcare team promptly substitutes the current broad-spectrum antibiotics with vancomycin, a more targeted approach to combat MRSA. This decision requires careful monitoring of the patient's renal function, as vancomycin can have nephrotoxic effects, especially crucial given the patient's diabetic status.

The nursing team also notes a slight increase in the patient's blood glucose levels, now consistently above 200 mg/dL despite his usual insulin regimen. Recognizing the impact of stress and infection on glycemic control, the nursing staff collaborates with the endocrinology team to adjust the patient's insulin dosage. This adjustment aims to maintain optimal blood glucose levels, which is critical for effective wound healing and reducing the risk of further complications. The healthcare team remains vigilant, continuously reassessing the patient's condition and ensuring that all interventions align with the evolving clinical picture.

Section 3

As the nursing team closely monitors the patient's response to the adjusted treatment regimen, new diagnostic results reveal additional complications that require immediate attention. A follow-up blood culture confirms bacteremia, indicating that the MRSA infection has entered the bloodstream. This finding heightens the urgency of the situation, as systemic infection poses a significant threat to the patient's overall stability. Further laboratory tests reveal a rising white blood cell count, now at 15,000/mm³, suggesting a persistent inflammatory response despite the targeted antibiotic therapy. In conjunction with the bacteremia, these results necessitate an interdisciplinary approach to refine the current treatment plan and prevent the progression to full-blown sepsis.

The patient's renal function is also carefully evaluated given the initiation of vancomycin. Serum creatinine levels, which were initially stable, show a slight increase to 1.4 mg/dL, prompting the healthcare team to assess the need for adjusting the vancomycin dosage or frequency. Additionally, the patient's urine output has decreased, and he reports a new onset of flank pain, raising concerns about potential nephrotoxicity. These symptoms necessitate a comprehensive review of the patient's medication and fluid management to safeguard renal health while effectively addressing the infection.

Given the complexity of the patient's condition, the nursing staff implements a more rigorous monitoring protocol, including more frequent assessments of vital signs, renal function, and pain management strategies. The team also emphasizes the importance of maintaining strict hand hygiene and implementing contact precautions to prevent further transmission of MRSA within the healthcare setting. As the patient's journey continues, the focus remains on stabilizing his systemic condition, optimizing antibiotic therapy, and mitigating any additional risks posed by his comorbid diabetes, which continues to complicate glycemic control. This intricate balance of interventions underscores the critical role of clinical reasoning in navigating the evolving challenges presented by this case.

Section 4

The nursing team observes a change in the patient's status, marked by a sudden increase in heart rate to 110 beats per minute and a drop in blood pressure to 88/60 mmHg, raising concerns about potential sepsis. The patient also appears increasingly lethargic and exhibits confusion, a deviation from his baseline mental status. These symptoms, alongside the confirmed bacteremia and elevated white blood cell count, suggest a progression towards systemic infection. In response, the healthcare team initiates a sepsis protocol, which includes administering a fluid bolus of normal saline to address potential hypovolemia and reassessing the antibiotic regimen to ensure optimal coverage against MRSA.

Concurrent with these developments, the patient's blood glucose levels become more erratic, with readings fluctuating between 60 mg/dL and 220 mg/dL. This variability complicates glycemic control and poses additional risks, given the patient's diabetes. The interdisciplinary team collaborates to adjust the patient's insulin regimen, aiming to stabilize blood glucose levels while minimizing the risk of hypoglycemia. This adjustment involves a careful reevaluation of the patient's nutritional intake and timing of insulin administration, guided by frequent blood glucose monitoring.

Amid these interventions, the nursing staff remains vigilant in monitoring for any signs of further deterioration, such as increased respiratory rate or decreased urine output, which could indicate worsening renal function or respiratory compromise. The team also continues to emphasize infection control practices, recognizing the importance of preventing further spread of MRSA within the healthcare environment. As the patient's condition remains precarious, the focus is on maintaining a delicate balance between aggressive treatment of the systemic infection and careful management of comorbid conditions, underscoring the critical role of ongoing clinical assessment and adjustment of the care plan.

Section 5

As the situation unfolds, the nursing team conducts a comprehensive reassessment of the patient, paying particular attention to potential signs of respiratory compromise. The assessment reveals an increased respiratory rate of 28 breaths per minute, accompanied by shallow breathing and mild accessory muscle use, suggesting the onset of respiratory distress. Oxygen saturation levels have decreased slightly to 92% on room air, prompting the team to initiate supplemental oxygen via nasal cannula at 2 liters per minute to maintain adequate oxygenation. Auscultation of the lungs reveals diminished breath sounds at the bases, raising concerns about potential atelectasis or early pneumonia, which could further exacerbate the patient's condition.

Concurrent with the respiratory concerns, the patient's urine output has decreased to 20 mL/hour over the past four hours, indicating possible worsening renal function. This oliguria, along with the patient's hypotensive state, suggests a risk for acute kidney injury, likely secondary to the sepsis-induced hypoperfusion. The team reviews the patient's fluid balance and adjusts the fluid management plan to include additional IV fluids, carefully balancing the risk of fluid overload against the need for adequate perfusion.

The interdisciplinary team also notes a concerning trend in the patient's laboratory results, with a rising creatinine level now at 2.1 mg/dL, up from 1.3 mg/dL earlier in the admission, reinforcing the suspicion of renal impairment. The team collaborates to adjust medications that are renally cleared and considers the need for nephrology consultation. This evolving clinical picture underscores the complexity of managing a critically ill patient with burns, sepsis, and diabetes, emphasizing the need for vigilant monitoring, timely interventions, and dynamic adjustment of the care plan to address new complications as they arise.