Hypertension - Nursing Case Study
Pathophysiology
• Primary mechanism: Increased peripheral vascular resistance is a crucial factor in hypertension. It occurs when blood vessels constrict, often due to factors like stress, high sodium intake, or genetic predisposition, leading to higher blood pressure as the heart works harder to pump blood through narrower vessels.
• Secondary mechanism: Overactivation of the renin-angiotensin-aldosterone system (RAAS) plays a significant role. This system, when overactive, increases sodium and water retention, and causes vasoconstriction, further raising blood pressure levels.
• Key complication: Chronic hypertension can lead to target organ damage, such as hypertensive heart disease. This condition results from the heart working against high resistance, leading to left ventricular hypertrophy and potentially progressing to heart failure if unmanaged.
Patient Profile
Demographics:
52-year-old male, office manager
History:
• Key past medical history: Hypertension diagnosed 5 years ago, family history of cardiovascular disease
• Current medications: Lisinopril 20 mg daily, Hydrochlorothiazide 25 mg daily
• Allergies: Penicillin
Current Presentation:
• Chief complaint: Increasing headaches and dizziness
• Key symptoms: Fatigue, occasional chest discomfort, blurred vision
• Vital signs: Blood pressure 162/98 mmHg, heart rate 88 bpm, respiratory rate 18 breaths per minute, temperature 98.6°F
Section 1
During the initial assessment, the nurse notes that the patient appears anxious and slightly diaphoretic. Upon auscultation, an S4 heart sound is detected, indicating possible left ventricular hypertrophy due to chronic high blood pressure. The nurse also observes mild bilateral edema in the patient's lower extremities. Given the patient's complaints of blurred vision, a fundoscopic examination is performed, revealing signs of hypertensive retinopathy, including arteriovenous nicking and cotton wool spots. These findings suggest that the patient is experiencing target organ damage secondary to poorly controlled hypertension.
A set of laboratory tests is ordered to further evaluate the patient's condition. The results show elevated serum creatinine levels of 1.8 mg/dL, indicating potential renal impairment. The patient's lipid profile reveals elevated LDL cholesterol at 150 mg/dL and decreased HDL cholesterol at 38 mg/dL, which increases cardiovascular risk. An EKG shows evidence of left ventricular hypertrophy, further supporting the physical examination findings. These results highlight the need for a comprehensive treatment plan to address not only the elevated blood pressure but also the emerging complications affecting the heart, eyes, and kidneys.
The healthcare team discusses the case, considering possible adjustments to the patient's medication regimen. Increasing the dose of Lisinopril or adding another antihypertensive agent such as a calcium channel blocker is considered to achieve better blood pressure control and reduce the risk of further organ damage. Additionally, lifestyle modifications, including dietary changes to reduce sodium intake and a structured exercise program, are recommended to the patient. The team emphasizes the importance of regular follow-up appointments to monitor blood pressure and assess the effectiveness of the treatment plan, aiming to prevent progression to more severe complications like heart failure or chronic kidney disease.
Section 2
Two weeks after the initial assessment and implementation of the treatment plan, the patient returns for a follow-up appointment. The nurse notes that the patient appears less anxious, but the mild bilateral edema in the lower extremities persists. The patient reports adhering to the prescribed lifestyle modifications, including a low-sodium diet and walking for 30 minutes daily. However, the patient mentions occasional dizziness and a persistent headache, raising concerns about effective blood pressure management.
Vital signs are assessed, revealing a blood pressure of 160/100 mmHg, which remains elevated despite the current treatment regimen. Heart rate is 78 beats per minute, and respirations are 16 per minute. The nurse performs a repeat fundoscopic examination, which still shows arteriovenous nicking and cotton wool spots, suggesting ongoing hypertensive retinopathy. A repeat blood test indicates that serum creatinine has increased to 2.0 mg/dL, confirming the progression of renal impairment. The lipid profile shows slight improvement, with LDL cholesterol reduced to 140 mg/dL, but HDL cholesterol remains low at 40 mg/dL.
Given these findings, the healthcare team discusses potential adjustments to the patient's treatment plan. The team decides to add a calcium channel blocker to the medication regimen to help achieve better blood pressure control. Additionally, they consider the possibility of underlying secondary causes of hypertension, such as renal artery stenosis, which may necessitate further investigation. The team reiterates the importance of regular monitoring and follow-up appointments, emphasizing that addressing the hypertension more aggressively is crucial to prevent further target organ damage and avoid progression to more severe complications, such as chronic kidney disease or heart failure.
Section 3
Two weeks after the introduction of the calcium channel blocker to the treatment regimen, the patient returns for another follow-up appointment. During the initial assessment, the nurse notes that the patient appears more fatigued and reports experiencing increased episodes of dizziness, particularly upon standing, which suggests potential orthostatic hypotension. The patient also mentions a new onset of palpitations and intermittent chest discomfort, raising concerns about cardiovascular implications.
Vital signs reveal a blood pressure of 150/95 mmHg, showing a slight improvement but still not at target levels. Heart rate is elevated at 92 beats per minute, and respirations remain steady at 18 per minute. Upon physical examination, the nurse detects a mild irregularity in the heart rhythm, prompting further investigation. An electrocardiogram is performed, revealing occasional premature ventricular contractions (PVCs), which may be a side effect of the medication or indicative of underlying cardiac issues.
In light of these findings, the healthcare team reviews the patient's current medications and considers adjusting dosages or exploring alternative antihypertensive agents to mitigate side effects while effectively managing blood pressure. The team also decides to conduct additional diagnostic testing, including an echocardiogram, to evaluate cardiac function and rule out structural heart disease. This approach aims to address the patient's symptoms comprehensively and prevent the progression of cardiovascular complications, ensuring a more stable and safe treatment pathway.
Section 4
Following the initial assessment and electrocardiogram findings, the healthcare team proceeds with an echocardiogram to gain further insights into the patient's cardiac function. The echocardiogram reveals mild left ventricular hypertrophy and a slightly reduced ejection fraction of 48%, suggesting early signs of heart failure. These results indicate that the patient's hypertension may have begun causing structural changes in the heart, necessitating a more aggressive and tailored treatment strategy to prevent further deterioration.
In response to these diagnostic results, the healthcare team decides to initiate lifestyle modification counseling focused on dietary changes, such as a low-sodium diet, and increased physical activity, tailored to the patient's capabilities and limitations. Pharmacologically, a low-dose beta-blocker is added to the regimen to address the palpitations and reduce cardiac workload, while the dosage of the calcium channel blocker is carefully reassessed to minimize side effects. The patient is educated on recognizing signs of worsening heart failure, such as increased shortness of breath or swelling, and instructed to report any concerning symptoms immediately.
As the patient begins this adjusted treatment plan, regular follow-ups are scheduled to closely monitor blood pressure, heart rate, and overall well-being. The healthcare team remains vigilant for any new symptoms or complications, prepared to make further adjustments as needed to optimize the patient's cardiovascular health and quality of life. This proactive approach emphasizes ongoing assessment and intervention, with the goal of stabilizing the patient's condition and preventing future cardiovascular events.
Section 5
As the patient adheres to the adjusted treatment plan, the healthcare team notes initial improvements in blood pressure control, with readings now averaging 135/85 mmHg during follow-up visits. The patient's heart rate has stabilized to a range of 70-75 beats per minute, suggesting a favorable response to the low-dose beta-blocker. However, during a routine follow-up, the patient reports experiencing episodes of dizziness, particularly when standing up quickly, as well as mild fatigue. These symptoms raise concerns about potential orthostatic hypotension or an adverse reaction to the new medication regimen, prompting the healthcare team to conduct further evaluation.
A physical examination reveals postural blood pressure changes, with a drop of 15 mmHg in systolic pressure upon standing, indicative of orthostatic hypotension. Laboratory tests are ordered to assess electrolyte levels, renal function, and complete blood count, revealing a mild hyponatremia with a sodium level of 133 mmol/L and a slight elevation in creatinine at 1.4 mg/dL, potentially linked to both the dietary changes and medication effects. These findings necessitate careful consideration of the current pharmacological approach, as well as a re-evaluation of the patient's hydration and nutritional status.
In response to these developments, the healthcare team decides to adjust the patient's medication regimen by reducing the dose of the beta-blocker and providing guidance on managing posture changes to mitigate dizziness. Additionally, dietary recommendations are revisited to ensure adequate sodium intake while still maintaining overall cardiovascular health. The patient is advised to monitor their symptoms closely and continue regular follow-ups to reassess blood pressure and electrolyte balance. This nuanced approach aims to balance effective hypertension management with minimizing side effects, highlighting the importance of individualized care and continuous clinical reasoning.