alzheimers - Nursing Case Study

Pathophysiology

• Primary mechanism: Accumulation of beta-amyloid plaques in the brain; these sticky protein fragments clump together between neurons, disrupting cell communication and triggering inflammation.

• Secondary mechanism: Formation of neurofibrillary tangles made of tau protein inside neurons; these tangles cause structural collapse within nerve cells, leading to cell death and loss of brain tissue.

• Key complication: Progressive neuronal damage and loss lead to cognitive decline, memory loss, and impaired daily functioning, hallmark symptoms of Alzheimer's disease.

Patient Profile

Demographics:

72-year-old female, retired school teacher

History:

• Key past medical history: Hypertension, hyperlipidemia

• Current medications: Lisinopril 10 mg daily, Atorvastatin 20 mg daily

• Allergies: None

Current Presentation:

• Chief complaint: Mild memory lapses

• Key symptoms: Occasional forgetfulness, difficulty recalling recent events, no significant impact on daily functioning

• Vital signs: Blood pressure 128/78 mmHg, heart rate 72 bpm, respiratory rate 16/min, temperature 98.6°F

Section 1

Initial Assessment Findings:

During the initial assessment, the nurse conducts a thorough evaluation of the 72-year-old retired school teacher's cognitive and functional status. The patient is alert and oriented to person, place, and time but demonstrates some difficulty with short-term memory tasks. For instance, she struggles to recall the names of new acquaintances and occasionally misplaces everyday items such as keys and glasses. The nurse performs a Mini-Mental State Examination (MMSE) and notes a score of 26 out of 30, indicating mild cognitive impairment. The patient is cooperative and expresses some frustration about her forgetfulness, stating that it "comes and goes," but she is still able to manage her daily activities independently.

The nurse also assesses the patient's ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs). The patient reports no difficulty with basic self-care tasks such as bathing, dressing, or feeding. However, she mentions that she requires written reminders to help manage her medication schedule effectively and occasionally needs assistance with complex tasks like managing finances. The patient's physical examination reveals no new abnormalities, and her vital signs remain stable, with a blood pressure of 128/78 mmHg and a heart rate of 72 bpm.

These findings align with the early stage of Alzheimer's disease, where cognitive deficits are mild and do not yet significantly impair daily functioning. The nurse discusses the importance of routine monitoring and maintaining a structured daily routine to support cognitive function. The patient is encouraged to engage in mentally stimulating activities and is provided with educational materials about Alzheimer's disease progression and management strategies. The nurse plans to follow up regularly to monitor the patient's cognitive status and adjust care plans as needed.

Section 2

Response to Interventions:

Several weeks after the initial assessment, the nurse conducts a follow-up visit to evaluate the patient's response to the interventions recommended for managing her early-stage Alzheimer's disease. The patient reports that she has incorporated several strategies into her daily routine, including using a calendar and setting reminders on her phone to assist with medication management. She has also started participating in a weekly book club at the local library, which she finds both enjoyable and mentally stimulating. The patient expresses that these adjustments have helped her feel more organized and less frustrated with her forgetfulness.

During this visit, the nurse reassesses the patient's cognitive and functional status. The patient remains alert and oriented, with no significant changes in her ability to perform ADLs and IADLs independently. However, she continues to need occasional reminders for more complex tasks, such as paying bills. The nurse conducts another Mini-Mental State Examination (MMSE), noting a stable score of 26 out of 30, indicating that the patient's cognitive impairment has not progressed. Vital signs are consistent with previous findings, with a blood pressure of 126/80 mmHg and a heart rate of 70 bpm. These stable results suggest that the interventions and support systems in place are effectively maintaining her current level of functioning.

The nurse discusses the importance of ongoing engagement in mentally stimulating activities and maintaining social connections as part of the patient's care plan. Additionally, the nurse emphasizes the value of regular follow-up visits to monitor any changes in cognitive status and to adjust care strategies as necessary. The patient is encouraged to continue using her support network, including family and friends, to aid in managing her condition. The nurse plans to schedule the next follow-up in three months, with instructions to reach out sooner if the patient experiences any changes in her cognitive abilities or daily functioning.

Section 3

Three months after the last follow-up, the nurse visits the patient to evaluate her ongoing response to interventions for early-stage Alzheimer’s disease. During this visit, the patient shares that she has been experiencing occasional episodes of mild confusion, particularly in the late afternoon, which her daughter describes as "sundowning." Despite these episodes, the patient remains independent in her daily activities, with her daughter providing support as needed. The patient continues to engage in her routine activities, including the weekly book club, although she occasionally forgets details of the discussions.

The nurse conducts a thorough assessment, noting a slight decline in the patient's Mini-Mental State Examination (MMSE) score to 24 out of 30, signaling a mild progression of cognitive impairment. The patient's vital signs remain stable, with a blood pressure of 124/78 mmHg and a heart rate of 72 bpm. Laboratory tests reveal no significant changes in her metabolic panel, and her vitamin B12 and thyroid function tests are within normal limits, ruling out metabolic causes for the increased confusion.

In response to these findings, the nurse discusses the importance of maintaining a structured daily routine to help minimize confusion, especially during the late afternoon and evening. The patient and her daughter are advised on strategies to manage sundowning, such as ensuring adequate rest during the day, reducing caffeine intake, and keeping the environment well-lit in the evening. The nurse emphasizes the need to monitor the patient closely for any further changes in cognitive or functional status and schedules the next follow-up visit in two months. Additionally, the nurse encourages the patient to remain engaged with her support network and to report any new symptoms promptly. This approach aims to maintain the patient’s quality of life and address challenges as they arise.

Section 4

Two months later, during the scheduled follow-up visit, the nurse finds the patient in a cheerful mood, sitting with her daughter in the living room. The patient reports that she has been following the structured routine suggested by the nurse, and both she and her daughter have noticed fewer episodes of late afternoon confusion. The patient has also started using a daily planner, which has helped her keep track of appointments and social activities, including her weekly book club meetings. Her daughter mentions that the patient seems more confident and less anxious about forgetting things, which has improved her overall mood.

The nurse performs a reassessment, noting that the patient's Mini-Mental State Examination (MMSE) score remains stable at 24 out of 30. The patient's vital signs continue to be within normal ranges, with a blood pressure of 126/80 mmHg and a heart rate of 70 bpm. The patient reports feeling physically well, with no new symptoms. The nurse discusses the importance of continued engagement in social and cognitive activities, as these have been beneficial in maintaining her cognitive function and quality of life.

Encouraged by the positive response to the interventions, the nurse reinforces the strategies for managing sundowning and suggests incorporating light physical exercises, such as walking or yoga, which can further enhance mood and cognitive health. The patient and her daughter are reminded to maintain open communication with the healthcare team and to monitor for any subtle changes in behavior or cognition. The nurse schedules the next follow-up visit in three months, with the goal of maintaining the patient's current level of function and ensuring a supportive environment for managing early-stage Alzheimer's disease.

Section 5

Three months later, during the scheduled follow-up visit, the nurse notes a slight change in the patient's status. Although the patient still appears cheerful and engaged, her daughter mentions noticing increased episodes of repetitive questioning and occasional difficulty in recalling names of familiar acquaintances. The patient herself admits feeling slightly more forgetful but brushes it off as normal aging. The nurse uses this opportunity to conduct another Mini-Mental State Examination (MMSE), which shows a minor decline to a score of 22 out of 30.

The patient's vital signs remain stable with a blood pressure of 124/82 mmHg and a heart rate of 72 bpm. Physical examination does not reveal any new findings, and the patient reports no physical discomfort. Laboratory tests conducted prior to the visit show normal blood glucose and cholesterol levels, but there is a mild deficiency in vitamin B12, which can occasionally contribute to cognitive decline. The nurse discusses the importance of addressing this deficiency and suggests dietary adjustments and possibly vitamin supplements, while also emphasizing the continued use of the daily planner and participation in social and cognitive activities.

The nurse advises that although slight fluctuations in cognitive function can occur, it's crucial to monitor these changes closely. The patient and her daughter are encouraged to keep a detailed record of any further cognitive changes and to stay in regular contact with the healthcare team. The nurse sets up another follow-up appointment in three months and highlights the importance of maintaining a balanced diet, regular physical activity, and social engagement to support the patient's cognitive health. This visit concludes with a shared plan to reassess the need for any medication adjustments or additional support based on the patient's ongoing response to the current interventions.