Borderline Personality Disorder - Nursing Case Study

Pathophysiology

• Primary mechanism: Emotional Dysregulation - Individuals with Borderline Personality Disorder (BPD) often experience heightened emotional sensitivity and intense emotional responses. This is linked to dysfunctions in brain areas like the amygdala and prefrontal cortex, impairing emotion regulation and leading to rapid mood swings.

• Secondary mechanism: Impaired Interpersonal Relationships - BPD is characterized by unstable and intense relationships, often due to an intense fear of abandonment and difficulty in maintaining a stable self-image. This instability is partly due to altered serotonin function affecting mood and impulsivity.

• Key complication: Increased Risk for Self-Harming Behaviors - Due to intense emotional distress and impulsivity, individuals with BPD may engage in self-harm or suicidal behaviors as maladaptive coping mechanisms, requiring vigilant clinical assessment and management.

Patient Profile

Demographics:

28-year-old female, freelance graphic designer

History:

• Key past medical history: Diagnosed with Borderline Personality Disorder at age 24; history of self-harm and unstable relationships.

• Current medications: Sertraline 100 mg daily, Quetiapine 50 mg at bedtime.

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Increasing mood swings and feelings of emptiness.

• Key symptoms: Emotional instability, fear of abandonment, frequent anger outbursts, intermittent self-harming behavior.

• Vital signs: Blood pressure 140/90 mmHg, heart rate 102 bpm, temperature 98.6°F, respiratory rate 18 breaths per minute.

Section 1

New Complications:

As the healthcare team continues to monitor the 28-year-old patient, they notice a concerning pattern in her recent behavior that suggests emerging complications. The patient reports increased frequency and severity of her emotional outbursts, which now occur multiple times a day and are often triggered by minor stressors. Additionally, she describes a heightened sense of depersonalization during these episodes, feeling disconnected from her own body and actions. This has led to more frequent instances of self-harming behavior, despite already being on a daily regimen of Sertraline and Quetiapine. Her partner, who accompanies her to the clinic, expresses concern over the patient's growing inability to maintain her freelance work commitments, noting that she often locks herself in a room for hours, overwhelmed by feelings of worthlessness and inadequacy.

Clinically, her recent lab work indicates a slight but notable increase in her liver enzymes, which raises a red flag for potential medication-related side effects. Her vital signs consistently show elevated blood pressure and heart rate, with readings averaging 145/92 mmHg and 108 bpm, respectively. These findings suggest a physiological stress response that may be exacerbating her emotional dysregulation. The healthcare team is also concerned about her sleep patterns; the patient reports difficulty falling asleep and frequent nocturnal awakenings, which likely contribute to her daytime irritability and cognitive difficulties.

Given these developments, the team considers adjusting her medication regimen and initiating a more intensive therapeutic approach, potentially incorporating dialectical behavior therapy (DBT) to better address her emotional and interpersonal challenges. Additionally, the team plans to closely monitor her liver function and consider a collaborative approach with a psychiatrist to evaluate the potential need for medication adjustment. These steps are crucial in preventing further deterioration and ensuring a holistic approach to managing her BPD symptoms effectively.

Section 2

As the healthcare team implements the adjusted treatment plan, they initiate a comprehensive assessment to better understand the patient's current status and to guide therapeutic interventions. During this assessment, the patient exhibits increased anxiety and agitation, particularly when discussing her recent emotional episodes and work-related stress. Her partner contributes valuable insights, noting that the patient's emotional outbursts have become more unpredictable and are now often accompanied by intense crying spells and verbal aggression. This behavior has strained their relationship and increased the patient's feelings of isolation and guilt.

Physically, the patient appears fatigued, with dark circles under her eyes and a disheveled appearance, reflecting her ongoing sleep disturbances. Repeated assessments of her vital signs show persistently elevated blood pressure and heart rate, with readings now averaging 150/95 mmHg and 112 bpm. The team hypothesizes that these physiological responses may be linked to heightened emotional stress and inadequate coping mechanisms. Recent lab results further reveal an elevation in liver enzymes, specifically ALT and AST, suggesting a potential adverse reaction to her current medication regimen.

In response to these findings, the healthcare team considers several changes to her treatment plan. They prioritize an urgent psychiatric consultation to review her medication, exploring options such as reducing or substituting the dosages of her current medications to mitigate liver strain. Concurrently, the team emphasizes the importance of initiating dialectical behavior therapy (DBT) sessions, aiming to equip the patient with effective emotional regulation and distress tolerance skills. This integrated approach, combining medical management with targeted psychotherapy, seeks to stabilize her condition and enhance her capacity to manage stress, ultimately improving her quality of life and interpersonal relationships.

Section 3

The healthcare team arranges for a follow-up psychiatric consultation to address the patient's medication regimen, given the concern over elevated liver enzymes. During this session, the psychiatrist identifies that the patient has been on a high dose of valproate, which could be contributing to her liver function abnormalities. The psychiatrist recommends tapering the valproate while introducing lamotrigine, known for its mood-stabilizing properties and lower hepatic impact. Additionally, low-dose propranolol is prescribed to help manage her elevated heart rate and anxiety symptoms. These adjustments aim to alleviate physical symptoms while minimizing further hepatic strain.

Meanwhile, the patient begins attending weekly dialectical behavior therapy (DBT) sessions. Early in these sessions, she expresses skepticism about therapy's effectiveness, reflecting her ongoing distrust and fear of change. However, as the sessions progress, she starts to engage more actively, particularly in learning mindfulness and distress tolerance techniques. The therapist notices a gradual improvement in the patient's ability to articulate her emotions without escalating to verbal aggression. Her partner reports slight improvements in their interactions, noting fewer incidents of sudden emotional outbursts at home.

Despite these positive steps, new complications emerge as the patient reports episodes of severe dizziness and occasional tremors, potentially linked to the introduction of lamotrigine. The healthcare team conducts a thorough assessment, revealing that the patient's blood pressure has dropped to 110/70 mmHg, and her heart rate has stabilized but remains slightly elevated at 88 bpm. Concerned about these side effects, the psychiatrist decides to adjust the medication dosage while maintaining close monitoring. This careful balancing act between managing psychiatric symptoms and minimizing side effects underscores the complexity of treating borderline personality disorder, requiring ongoing clinical reasoning and adaptability in the treatment plan.

Section 4

As the healthcare team continues monitoring the patient closely, they notice a change in her status that warrants further investigation. Over the course of several days, the patient begins to exhibit signs of increased fatigue and confusion, alongside episodes of severe dizziness. During a routine check-up, the nurse observes that the patient’s coordination seems slightly impaired, and she struggles to maintain her balance while walking. Concerned about these developments, the team decides to conduct a set of diagnostic tests to identify any underlying causes.

The laboratory results reveal a decrease in the patient's serum sodium levels, indicating hyponatremia with a value of 128 mEq/L. Her electrolyte imbalance could potentially be exacerbated by the recent introduction of lamotrigine, which is known to affect sodium channels. The team also notes a slight elevation in her liver enzymes, though not as severe as previously recorded. The patient's blood pressure remains low at 105/68 mmHg, and her heart rate has slightly decreased to 82 bpm. These findings suggest that while the introduction of lamotrigine has helped stabilize her heart rate, it may be contributing to her electrolyte imbalance and associated symptoms.

In response to these new complications, the psychiatrist collaborates with the healthcare team to reevaluate the patient’s medication regimen. They consider adjusting the lamotrigine dosage and increasing her fluid and electrolyte intake to address the hyponatremia. Concurrently, the team emphasizes the importance of regular monitoring and patient education to ensure adherence and timely detection of any adverse effects. The ongoing challenge lies in balancing the management of her psychiatric symptoms with the minimization of side effects, requiring careful clinical reasoning and a personalized approach to her care plan. As the patient navigates these adjustments, her engagement in DBT becomes even more crucial, providing her with the emotional tools necessary to cope with the physical and psychological complexities of her condition.

Section 5

As the healthcare team implements the adjusted treatment plan, they closely monitor the patient's response to the interventions for her hyponatremia and medication regimen. Over the next few days, there is a noticeable improvement in her electrolyte levels, with her serum sodium rising to 132 mEq/L. This gradual correction is accompanied by a reduction in her symptoms of fatigue and dizziness, suggesting a positive response to the increased fluid intake and adjusted lamotrigine dosage. However, the team remains vigilant for any new side effects, particularly given the complexity of her condition and the potential interactions between her psychiatric and physical health needs.

During routine monitoring, the nurse observes that the patient’s coordination and balance have improved, allowing her to walk with more confidence. Her blood pressure stabilizes slightly at 110/70 mmHg, and her heart rate remains consistent at 80 bpm. These stable vital signs provide reassurance that the adjustments are having the desired effect without overwhelming her system. Nevertheless, the healthcare team continues to prioritize regular assessments and patient education, emphasizing the importance of adherence to the fluid and dietary recommendations to prevent future electrolyte imbalances.

Despite these improvements, the patient begins to express increased anxiety about her health, which becomes a focal point during her Dialectical Behavioral Therapy (DBT) sessions. Recognizing the impact of her emotional state on her overall well-being, the psychiatrist collaborates with the DBT therapist to incorporate strategies that specifically address her health-related fears. This holistic approach aims to empower the patient to manage her anxiety, ensuring that her psychological resilience is strengthened alongside her physical recovery. As the patient progresses, the team remains committed to a dynamic care plan that adapts to her evolving needs, laying the groundwork for the next phase of her treatment journey.