urosepsis - Nursing Case Study

Pathophysiology

• Primary mechanism: Urosepsis begins with a urinary tract infection (UTI) where bacteria enter and multiply in the urinary system, often due to incomplete emptying of the bladder or catheter use. The infection can ascend to the kidneys, causing pyelonephritis, which significantly increases the risk of bacteria entering the bloodstream.

• Secondary mechanism: Once bacteria enter the bloodstream, they trigger a systemic inflammatory response, leading to widespread inflammation and the release of cytokines. This can cause vasodilation, increased vascular permeability, and potential organ dysfunction due to reduced blood flow and oxygen delivery.

• Key complication: The systemic inflammation and resulting hypotension can lead to septic shock, characterized by a severe drop in blood pressure, leading to multi-organ failure if not promptly treated. Early recognition and intervention are crucial for patient outcomes.

Patient Profile

Demographics:

67-year-old female, retired school teacher

History:

• Key past medical history: Hypertension, history of recurrent urinary tract infections

• Current medications: Lisinopril 10 mg daily, Hydrochlorothiazide 25 mg daily

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Fever and dysuria

• Key symptoms: Fever of 100.4°F (38°C), mild lower abdominal discomfort, increased urinary frequency and urgency

• Vital signs: Temperature 100.4°F (38°C), heart rate 88 bpm, blood pressure 130/78 mmHg, respiratory rate 16 breaths per minute, oxygen saturation 98% on room air

Section 1

Initial Assessment Findings:

As the nurse begins the initial assessment, they note that the patient, Ms. Johnson, appears mildly uncomfortable but is alert and oriented to person, place, and time. Upon further examination, the nurse finds mild suprapubic tenderness, which is consistent with her reported lower abdominal discomfort. The patient's skin is warm and dry, and she denies any flank pain or nausea. Despite the fever, Ms. Johnson has no signs of acute distress, and her respiratory function remains stable with an oxygen saturation of 98% on room air.

A focused assessment of the urinary system reveals that Ms. Johnson experiences increased urinary frequency and urgency, consistent with her history of recurrent UTIs. She reports that the dysuria began roughly two days ago and has progressively worsened. The nurse reviews the patient's medication list and confirms that Ms. Johnson is not currently taking any antibiotics for the UTI, as she was waiting to see her primary care physician.

Vital signs are rechecked, showing stability: heart rate at 88 bpm, blood pressure at 130/78 mmHg, and respiratory rate at 16 breaths per minute. The nurse notes the importance of maintaining close monitoring of these parameters, given the potential for urosepsis to progress. The nurse plans to collect a urine sample for urinalysis and culture to identify the causative organism and determine appropriate antibiotic therapy, keeping in mind the patient's penicillin allergy. In anticipation of the physician's orders, the nurse prepares to initiate fluid resuscitation to maintain adequate perfusion and prevent any potential complications associated with systemic infection.

Section 2

New Diagnostic Results:

As the nurse continues to care for Ms. Johnson, the results of the urinalysis and urine culture become available. The urinalysis reveals the presence of leukocytes and nitrites, consistent with a urinary tract infection. The urine culture identifies Escherichia coli as the causative organism, which is commonly associated with UTIs. Sensitivity testing indicates that the bacteria are susceptible to several antibiotics, including ciprofloxacin, which is a suitable option given Ms. Johnson's penicillin allergy.

With this information, the nurse communicates the results to the attending physician, who prescribes an oral course of ciprofloxacin. The nurse educates Ms. Johnson on the importance of completing the full course of antibiotics to effectively eradicate the infection and prevent recurrence. Additionally, the nurse advises Ms. Johnson to increase her fluid intake to help flush out the bacteria and to monitor for any worsening symptoms or side effects from the medication.

Recognizing the importance of early intervention, the nurse also assesses Ms. Johnson's understanding of her condition and the treatment plan. Ms. Johnson demonstrates comprehension and expresses a commitment to adhering to the prescribed regimen. The nurse plans to follow up with Ms. Johnson to ensure that her symptoms are improving and to reassess her vital signs and overall condition. This proactive approach aims to prevent progression to more severe complications such as full-blown sepsis, while reinforcing the foundational nursing concept of patient education and self-management.

Section 3

As the nurse continues to monitor Ms. Johnson, she notes that Ms. Johnson's vital signs are stable: her temperature is 98.6°F, heart rate is 78 beats per minute, respiratory rate is 18 breaths per minute, and blood pressure is 118/74 mmHg. However, Ms. Johnson reports experiencing mild nausea and a slight increase in frequency and urgency of urination since starting the ciprofloxacin. The nurse conducts a thorough assessment to determine if these symptoms are side effects of the medication or indicative of a complication. Ms. Johnson denies any flank pain, chills, or fever, which reassures the nurse that there is no immediate evidence of worsening infection.

In reviewing Ms. Johnson's laboratory results, the nurse notes that her white blood cell count is slightly elevated at 11,000/mm³, which is consistent with her body's response to the infection. Kidney function tests, including BUN and creatinine levels, remain within normal limits, suggesting that her renal function is not compromised. The nurse advises Ms. Johnson to take the antibiotic with food to help alleviate the nausea and continues to encourage increased fluid intake to support kidney function and help alleviate urinary symptoms.

The nurse plans to reassess Ms. Johnson's symptoms and side effects over the next 24 hours and educate her about signs of potential complications, such as rash or persistent gastrointestinal upset, which could necessitate a change in medication. By maintaining open communication and monitoring, the nurse aims to ensure that Ms. Johnson's treatment progresses smoothly and supports her recovery without further complications. This vigilance reinforces the nursing focus on early detection and intervention, ensuring patient safety and promoting therapeutic efficacy.

Section 4

The next morning, the nurse checks in with Ms. Johnson to reassess her condition and evaluate her response to the interventions. Ms. Johnson reports that her nausea has slightly improved since she started taking the ciprofloxacin with meals, and she has been diligently drinking more water as advised. Her urinary symptoms remain unchanged, with continued frequency and urgency, but no pain during urination. Vital signs are stable, with a temperature of 98.7°F, heart rate of 80 beats per minute, respiratory rate of 18 breaths per minute, and blood pressure of 116/76 mmHg. The nurse is reassured by the stability of these parameters but remains attentive to any subtle changes that could indicate a developing issue.

The nurse reviews the results of Ms. Johnson's latest urinalysis, which shows a decrease in the number of bacteria present, indicating a positive response to the antibiotic treatment. However, there is a slight increase in leukocyte esterase and white blood cells in the urine, suggesting ongoing irritation or inflammation of the urinary tract. Given this information, the nurse continues to emphasize the importance of completing the full course of antibiotics and maintaining adequate hydration. Ms. Johnson is educated about monitoring for any new symptoms, such as a return of fever, increased pain, or changes in urine color or smell, that would require immediate attention.

Throughout the day, the nurse remains vigilant, checking in periodically to ensure that Ms. Johnson is comfortable and that her symptoms are not worsening. The nurse also takes this opportunity to reinforce teaching about lifestyle adjustments that can support urinary health, such as avoiding irritants like caffeine and alcohol, wearing breathable cotton underwear, and practicing good personal hygiene. By the end of the shift, Ms. Johnson expresses gratitude for the clear communication and support, feeling more confident in managing her condition and recognizing when to seek further help. This proactive approach aligns with the nursing priority of patient education and empowerment, facilitating a smoother recovery process and preventing future complications.

Section 5

Later in the afternoon, the nurse notes a subtle change in Ms. Johnson's condition. While her vital signs remain stable, Ms. Johnson reports feeling slightly more fatigued than earlier, and her appetite has diminished. She mentions a mild, persistent headache that she attributes to not sleeping well the previous night. The nurse performs a thorough assessment, finding that Ms. Johnson's temperature remains normal at 98.6°F, her heart rate is steady at 82 beats per minute, respiratory rate is 18 breaths per minute, and blood pressure is 114/74 mmHg. Despite these stable signs, the nurse decides to review Ms. Johnson’s fluid intake to ensure she is adequately hydrated, suspecting that mild dehydration could contribute to her symptoms.

The nurse discusses with Ms. Johnson the importance of maintaining consistent fluid intake throughout the day, especially while her body is fighting the infection and adjusting to the antibiotics. Ms. Johnson admits she has been more focused on drinking water during meals but has not been as diligent between them. The nurse suggests setting reminders to take sips of water regularly and explains how proper hydration can alleviate fatigue and prevent headaches. Additionally, the nurse reassures Ms. Johnson that some fatigue can be expected as her body heals but emphasizes the need to monitor for any escalation in symptoms.

By evening, Ms. Johnson appears slightly more energetic after following the hydration advice, though she still feels some residual tiredness. The nurse concludes her shift by reiterating key points from the earlier education session, ensuring Ms. Johnson understands the importance of adherence to her treatment plan and lifestyle adjustments. With a comprehensive care approach, Ms. Johnson feels better prepared to manage her condition and recognizes the support system in place should her symptoms change, marking a positive step in her recovery journey.