Parkinson’s inpatient rehabilitation - Nursing Case Study

Pathophysiology

• Primary mechanism: Degeneration of dopaminergic neurons in the substantia nigra leads to decreased dopamine production, crucial for motor control, resulting in hallmark symptoms like tremors, rigidity, and bradykinesia.

• Secondary mechanism: Imbalance between dopamine and acetylcholine in the basal ganglia further disrupts motor function, exacerbating movement disorders and impairing coordination.

• Key complication: Neurodegeneration can extend beyond the motor system, leading to non-motor symptoms such as cognitive decline and mood disorders, which complicate rehabilitation efforts and require comprehensive nursing management.

Patient Profile

Demographics:

65-year-old male, retired engineer

History:

• Key past medical history: Diagnosed with Parkinson's disease 5 years ago, hypertension, type 2 diabetes

• Current medications: Levodopa-carbidopa, amantadine, metformin, lisinopril

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Increasing difficulty with mobility and balance

• Key symptoms: Tremors in both hands, bradykinesia, muscle stiffness, frequent falls, mild confusion

• Vital signs: Blood pressure 150/95 mmHg, heart rate 88 bpm, respiratory rate 22 breaths per minute, temperature 98.8°F

Section 1

New Complications:

During the second week of inpatient rehabilitation, the patient begins exhibiting signs of increased confusion and episodes of hallucinations. The nursing team notes that his tremors have also intensified, and his gait disturbance has worsened, leading to more frequent falls despite ongoing physical therapy. The patient's blood pressure has fluctuated, with occasional readings spiking to 160/100 mmHg, and he reports experiencing frequent headaches and dizziness. After a comprehensive assessment, the healthcare team suspects that these symptoms may be indicative of an adverse reaction to his current medication regimen, including potential side effects from the dopaminergic treatment.

The interdisciplinary team decides to conduct further diagnostic evaluations, including a complete blood count (CBC) and metabolic panel, to rule out any underlying infections or metabolic disturbances that could be contributing to his altered mental status. Results reveal mild hyponatremia with a sodium level of 130 mEq/L, which could be contributing to his cognitive symptoms. Additionally, renal function tests show a slight elevation in creatinine levels, prompting a review of his lisinopril dosage to address potential renal impairment. Recognizing the complexity of managing Parkinson’s disease with comorbid conditions, the team collaborates to adjust his medication plan, reducing the dosage of amantadine and closely monitoring his response.

The patient's care plan is updated to incorporate more frequent neurological assessments and a modified physical therapy regimen to enhance safety and prevent falls. Nursing staff is vigilant in monitoring for any further changes in mental status and motor function, aiming to stabilize his condition and improve his overall quality of life. This situation highlights the importance of continuous clinical reasoning and the need for a dynamic approach to managing the multifaceted challenges associated with Parkinson’s disease and its complications.

Section 2

As the healthcare team implements the adjusted medication regimen, they closely monitor the patient for changes in his condition. Within a few days, the nursing staff observes a noticeable reduction in the frequency of hallucinations and a slight improvement in his cognitive clarity. However, the patient's tremors and gait disturbances persist, and he continues to experience occasional falls. Physical therapists note that his postural instability seems to have increased, complicating the efforts to enhance his mobility and balance. Despite these challenges, the patient's blood pressure readings have stabilized somewhat, with occasional spikes, but generally remaining around 145/90 mmHg.

During this period, the patient experiences a new complication: he begins to develop dysphagia, experiencing difficulty swallowing, particularly with liquids. This raises concerns about potential aspiration and nutritional deficiencies. A speech therapist is consulted to assess his swallowing function and recommends a modified diet with thickened liquids and soft foods to minimize the risk of aspiration. Concurrently, the patient's dietary intake is carefully monitored to ensure adequate nutrition, and hydration status is closely observed to prevent further complications related to hyponatremia.

The interdisciplinary team recognizes the complexity of the patient's evolving condition and understands the need for ongoing adjustments to his care plan. They emphasize the importance of vigilant monitoring and timely interventions to prevent further complications. The patient and his family are involved in discussions about the new dietary modifications and are educated on the importance of adherence to these changes. This ongoing collaborative effort underscores the necessity of a dynamic, patient-centered approach in managing the intricate challenges associated with Parkinson's disease and its multifaceted complications. As the team remains focused on optimizing the patient's rehabilitation outcomes, they prepare for the possibility of further diagnostic evaluations and therapeutic adjustments as needed.

Section 3

As the interdisciplinary team continues to monitor the patient's progress, a new complication arises: the patient begins to exhibit signs of autonomic dysfunction, a common issue in advanced Parkinson's disease. The nursing staff notes that the patient experiences episodes of orthostatic hypotension, with blood pressure dropping to 95/60 mmHg when transitioning from lying to standing, causing dizziness and increasing the risk of falls. Additionally, he reports symptoms of urinary urgency and occasional incontinence, which are concerning for both the patient and his family. These developments prompt the healthcare team to conduct a thorough re-evaluation of his autonomic function.

In response to these changes, the medical team reviews the patient's current medication regimen to identify any drugs that may exacerbate his autonomic symptoms. They decide to adjust his Parkinson's medication dosage and introduce midodrine to manage his orthostatic hypotension. The team also collaborates with the patient and his family to implement non-pharmacological strategies, such as increasing fluid intake, wearing compression stockings, and practicing slow positional changes, to help mitigate his symptoms. Meanwhile, a urologist is consulted to assess and manage the urinary issues, ensuring that these do not contribute to further complications or impact his rehabilitation process.

These new challenges require the team to maintain a heightened level of vigilance and adaptability. The patient's response to these interventions will be closely observed, with regular monitoring of vital signs and reassessment of his functional status. The team remains committed to a holistic approach, integrating therapeutic adjustments with patient and family education to empower them in managing the disease's complexities. This phase of the patient's journey highlights the importance of a coordinated care strategy in addressing the evolving needs of individuals with Parkinson's disease, as the team anticipates further diagnostic evaluations to refine his treatment plan.

Section 4

Response to interventions

Following the implementation of both pharmacological and non-pharmacological strategies, the interdisciplinary team closely monitors the patient's response to the new interventions. Over the course of the next week, the nursing staff observes some stabilization in the patient's episodes of orthostatic hypotension. His blood pressure readings when transitioning from lying to standing improve slightly, averaging around 105/65 mmHg, though occasional dizziness still occurs. The patient reports a reduction in the frequency of urinary urgency, attributing this to the bladder training exercises introduced by the urologist. However, occasional incontinence persists, prompting the team to further explore potential strategies to address this issue.

The patient's family expresses concern about the persistence of some symptoms, particularly as these affect his confidence in participating fully in rehabilitation activities. The team reassures them, emphasizing that while progress may be gradual, the current interventions are yielding positive trends. Ongoing monitoring remains crucial, with the team adjusting the treatment plan based on daily assessments. The patient is encouraged to engage in seated exercises and balance training sessions tailored to his current capabilities, with the goal of enhancing his cardiovascular stability and reducing fall risk.

The team also places a strong emphasis on patient and family education, reinforcing the importance of adherence to recommended lifestyle modifications and medication regimens. They discuss potential signs of new or worsening symptoms, empowering the family to contribute actively to the patient's care. This collaborative approach not only addresses the current challenges but also prepares the family to manage future complexities associated with Parkinson’s disease. As the patient continues his rehabilitation journey, the team remains vigilant, poised to adapt the care plan as necessary to optimize his functional outcomes and quality of life.

Section 5

New Complications

As the patient continues his rehabilitation, the interdisciplinary team notices new complications impacting his progress. Despite the initial improvement in orthostatic hypotension, the patient begins experiencing increased episodes of bradykinesia, particularly in the mornings. This slowing of movement complicates his ability to participate in morning therapy sessions and increases the risk of falls. The patient's resting tremor also becomes more pronounced, affecting his ability to perform activities of daily living (ADLs) effectively. The team observes that his fine motor skills, such as buttoning a shirt or using utensils, have deteriorated, causing frustration for both the patient and his family.

In response to these developments, the team reviews the patient's medication regimen. A neurologist is consulted to evaluate the potential need for adjustments in his dopaminergic therapy. The goal is to achieve better control over motor symptoms without exacerbating side effects. They consider the timing of medication administration to optimize the patient's functional periods during the day. Additionally, the team introduces occupational therapy sessions focused on adaptive techniques and assistive devices to support his independence in daily activities.

Simultaneously, the patient's lab results reveal a mild anemia, with hemoglobin levels at 11.2 g/dL and hematocrit at 34%. This finding prompts the team to investigate potential causes, such as nutritional deficiencies or gastrointestinal bleeding, which could contribute to his fatigue and exacerbate bradykinesia. A dietary consultation is arranged to assess his nutritional intake and recommend appropriate interventions. As these new complications are addressed, the interdisciplinary team remains committed to adapting the care plan, ensuring a comprehensive approach that aligns with the evolving needs of the patient.