Lower GI Bleed - Nursing Case Study

Pathophysiology

• Primary mechanism: Diverticulosis - Outpouchings in the colon wall, known as diverticula, can erode blood vessels. When these vessels rupture, they cause acute bleeding, often presenting as painless hematochezia (bright red blood per rectum).

• Secondary mechanism: Angiodysplasia - Abnormal, fragile blood vessels in the GI tract, particularly the cecum and right colon, are prone to rupture due to increased pressure or wall stress, leading to episodic bleeding.

• Key complication: Hemodynamic instability - Significant blood loss can lead to hypovolemia, resulting in hypotension, tachycardia, and potential shock if not promptly managed.

Patient Profile

Demographics:

65-year-old male, retired construction worker

History:

• Key past medical history: Hypertension, diverticulosis, and coronary artery disease

• Current medications: Lisinopril, aspirin, and atorvastatin

• Allergies: Penicillin

Current Presentation:

• Chief complaint: Blood in stool and dizziness

• Key symptoms: Melena, fatigue, and abdominal cramping

• Vital signs: Blood pressure 98/60 mmHg, heart rate 115 bpm, respiratory rate 22 breaths per minute, temperature 99.1°F

Section 1

As the nursing team continues to monitor the patient, his condition begins to evolve. During a routine check, new lab results reveal a hemoglobin level of 8.2 g/dL, significantly lower than the normal range and indicating the severity of the ongoing bleed. The patient also starts to exhibit signs of orthostatic hypotension, fainting briefly when attempting to sit up. His blood pressure drops to 85/55 mmHg, and his heart rate escalates to 125 bpm, signaling worsening hemodynamic instability. The combination of these findings points towards acute blood loss anemia and the need for immediate intervention to prevent further complications.

In response to these alarming changes, the healthcare team initiates a blood transfusion protocol to stabilize his hemoglobin levels and improve oxygen carrying capacity. Simultaneously, IV fluids are administered to address hypovolemia and support blood pressure. Despite these interventions, the patient reports increased abdominal pain and a new onset of nausea, raising concerns about potential bowel ischemia due to prolonged hypotension. The nursing team promptly communicates these developments to the attending physician, who orders an urgent colonoscopy to identify the exact source of the bleed and assess for any ischemic damage in the bowel.

These developments prompt the healthcare team to prioritize a multidisciplinary approach, involving gastroenterology and potentially surgical consultation, to manage the lower GI bleed effectively. The clinical reasoning process now focuses on balancing the need for rapid intervention to control bleeding while preventing further complications such as ischemia or shock. The patient's response to the transfusion and fluid resuscitation will be crucial in determining the next steps, guiding the team towards potential endoscopic or surgical interventions if the bleeding source proves elusive or refractory to medical management.

Section 2

As the healthcare team continues to monitor the patient, they observe a change in his status following the initial interventions. Despite receiving a blood transfusion and IV fluids, the patient's heart rate remains elevated at 118 bpm, and his blood pressure stabilizes only slightly at 92/60 mmHg. He continues to experience dizziness and reports persistent fatigue, indicating that while there is some stabilization, the interventions have not fully resolved his hemodynamic instability. The patient’s abdominal pain persists, and he becomes increasingly anxious, which could further complicate his condition by increasing his heart rate and potentially exacerbating his bleeding.

In the wake of these developments, the team receives new lab results showing a marginal improvement in hemoglobin levels to 9.0 g/dL, yet his lactate levels have increased to 3.2 mmol/L, suggesting ongoing tissue hypoperfusion and a risk of lactic acidosis. Concerned about possible bowel ischemia, the attending physician orders an abdominal CT scan with contrast to better visualize any ischemic areas and to assess the extent of the bleed. The CT scan reveals thickening of the bowel wall in a segment of the descending colon, consistent with potential ischemic colitis. This finding prompts the team to involve a surgical consult to evaluate whether surgical intervention might be necessary.

These findings lead the healthcare team to re-evaluate their management strategy, emphasizing the importance of continuous monitoring and reassessment. The possibility of surgical intervention looms closer as the team prepares for potential escalation of care. Meanwhile, they ensure the patient is kept hydrated and comfortable, adjusting fluids and analgesics as needed while maintaining close observation for any signs of deterioration or further complications. This stage of the patient's journey highlights the critical role of timely diagnostics and interdisciplinary collaboration in managing complex cases of lower GI bleed with potential ischemic involvement.

Section 3

As the healthcare team continues to navigate the complexities of this case, the patient's condition takes a concerning turn. During the evening rounds, the nurse notices that the patient has developed a low-grade fever of 100.4°F (38°C) and his heart rate has increased further to 124 bpm. His blood pressure, however, remains relatively unchanged at 90/58 mmHg despite ongoing fluid resuscitation. On auscultation, his bowel sounds are hypoactive, and he reports increased abdominal pain, now rated at 8/10, which is more diffuse than before. Additionally, the patient appears more lethargic and intermittently confused, raising concerns about his neurological status.

In light of these changes, the team decides to perform repeat laboratory tests. The results reveal a further drop in hemoglobin to 8.5 g/dL and an increase in lactate levels to 4.0 mmol/L, indicating worsening tissue hypoperfusion. His white blood cell count has also risen to 15,000 cells/mm³, suggesting a possible inflammatory or infectious process. The combination of fever, leukocytosis, and abdominal pain heightens the suspicion of ischemic colitis progressing to bowel necrosis or perforation, which could explain the systemic inflammatory response and neurological changes.

Recognizing the urgency of the situation, the surgical team is consulted again, and a decision is made to prepare the patient for exploratory surgery. The goal is to assess the viability of the affected bowel segment, address potential areas of necrosis, and prevent further complications such as peritonitis or septic shock. Meanwhile, the medical team focuses on optimizing the patient's hemodynamic status, administering broad-spectrum antibiotics, and continuing supportive care to stabilize him as much as possible before the surgical intervention. This critical juncture underscores the importance of dynamic clinical assessment and timely decision-making in the management of complex lower GI bleed cases with suspected ischemic involvement.

Section 4

As preparations for the exploratory surgery continue, the healthcare team remains vigilant in monitoring the patient's response to interventions. Despite the administration of broad-spectrum antibiotics and aggressive fluid resuscitation, the patient's condition becomes increasingly precarious. Over the next hour, his heart rate climbs to 132 bpm, and his blood pressure dips further to 86/52 mmHg, indicating worsening hemodynamic instability. His respiratory rate increases to 28 breaths per minute, and his oxygen saturation begins to drop to 92% on room air, suggesting the onset of respiratory compromise possibly linked to systemic inflammatory response syndrome (SIRS).

The surgical team conducts a focused reassessment, noting increased abdominal distension and guarding, which could signal the progression of bowel ischemia to potential perforation. In response, the team escalates the patient's care, initiating a norepinephrine infusion to support blood pressure and improve perfusion. Concurrently, they order a STAT abdominal CT scan with contrast to better delineate the extent of bowel involvement and identify any signs of perforation that might necessitate an urgent operative approach.

As the CT results come through, they reveal significant wall thickening and pneumatosis intestinalis in the descending colon, along with free air under the diaphragm, confirming the presence of bowel perforation. This critical finding shifts the surgical plan from exploratory assessment to an immediate laparotomy to resect the necrotic segment and manage any contamination. The patient is swiftly transferred to the operating room, illustrating the need for prompt and decisive action in the face of rapidly evolving complications. The healthcare team remains focused on stabilizing the patient and mitigating the risk of septic shock, emphasizing the complexities inherent in managing advanced lower GI bleed cases with ischemic complications.

Section 5

As the surgical team prepares for the urgent laparotomy, the patient's condition continues to evolve, prompting a reassessment of his clinical status. During preoperative evaluation, the nurse notes that the patient's heart rate has increased further to 140 bpm, and his blood pressure remains low at 82/50 mmHg, despite the norepinephrine infusion. His respiratory rate is now at 30 breaths per minute, and oxygen saturation has decreased to 89% on 3 liters of oxygen via nasal cannula. His skin is cool and clammy, suggestive of peripheral vasoconstriction, and there is a notable decrease in urine output to 15 mL/hour over the last two hours, indicating potential acute kidney injury secondary to hypoperfusion.

Laboratory results return with a significant leukocytosis at 18,000/mm³, elevated lactate levels at 4.5 mmol/L, and a drop in hemoglobin to 7.2 g/dL, reflecting ongoing bleeding and metabolic stress. The elevated lactate is particularly concerning, as it indicates widespread tissue hypoxia, compounding the risk of septic shock. The team recognizes the need to transfuse red blood cells urgently to address the anemia and improve oxygen-carrying capacity. Additionally, the elevated white blood cell count and the presence of free air in the abdominal cavity heighten the suspicion of an evolving septic process, further complicating the clinical picture.

In the operating room, the surgical team proceeds with the laparotomy, discovering extensive necrosis in the descending colon with significant purulent contamination of the peritoneal cavity. The decision is made to resect the necrotic bowel segment and perform a temporary colostomy to divert fecal matter and facilitate healing. Throughout the procedure, the anesthesiologist diligently monitors hemodynamics, adjusting vasopressor support as necessary to maintain adequate perfusion. The intraoperative findings confirm the severity of the patient's condition, underscoring the importance of swift surgical intervention to prevent further deterioration. As the surgical team works to stabilize the patient, the focus shifts to postoperative management, aiming to control infection, restore hemodynamic stability, and support recovery in the intensive care unit.