Seizure - Nursing Case Study

Pathophysiology

• Primary mechanism: Seizures occur due to abnormal, excessive electrical activity in the brain's neurons, disrupting normal communication and leading to sudden, uncontrolled movements or changes in behavior.

• Secondary mechanism: This irregular electrical activity often results from an imbalance between excitatory and inhibitory neurotransmitters, such as glutamate and GABA, which affects the brain's ability to maintain normal function.

• Key complication: Prolonged or repeated seizures can lead to neuronal injury and increase the risk of developing epilepsy, where the brain becomes more prone to recurrent seizures.

Patient Profile

Demographics:

28-year-old female, software engineer

History:

• Key past medical history: Diagnosed with epilepsy 2 years ago, well-controlled with medication

• Current medications: Lamotrigine 100 mg twice daily

• Allergies: None

Current Presentation:

• Chief complaint: Brief episode of seizure at work

• Key symptoms: Loosening of consciousness for about 2 minutes, no postictal confusion, no tongue biting or incontinence

• Vital signs: Blood pressure 120/80 mmHg, heart rate 78 beats per minute, respiratory rate 16 breaths per minute, temperature 98.6°F, oxygen saturation 99% on room air

Section 1

Initial Assessment Findings:

Upon arriving at the emergency department, the 28-year-old female undergoes a thorough initial assessment by the nursing team. She appears alert and oriented, with no signs of distress. Her Glasgow Coma Scale score is a perfect 15, indicating full consciousness and awareness of her surroundings. The patient denies any headache, dizziness, or visual disturbances. Her speech is clear, and she is able to articulate the events leading up to the seizure episode at work, noting that she felt a brief sensation of déjà vu before losing consciousness.

A focused neurological examination reveals no focal deficits; her pupils are equal, round, reactive to light, and accommodation. Strength and sensation are intact in all extremities, and coordination tests, such as finger-to-nose and heel-to-shin, are performed without difficulty. While her vital signs remain stable, the nursing team notes a slight increase in heart rate to 82 beats per minute, which could be attributed to anxiety about the episode. The nurse also confirms the patient's compliance with her medication regimen, as she reports taking her lamotrigine as prescribed with no missed doses or recent changes.

To ensure comprehensive care, the nursing team initiates routine lab work to rule out any metabolic disturbances that could have triggered the seizure. Blood glucose levels are within normal limits, and electrolyte panels, including sodium and potassium, are unremarkable. These findings suggest that the seizure was likely an isolated breakthrough event rather than a result of an underlying acute condition. The patient is reassured, and education is provided on the importance of medication adherence and recognizing potential seizure triggers. As the assessment concludes, the medical team considers whether an adjustment to her medication dosage might be warranted to prevent future episodes.

Section 2

After the initial assessment, the medical team decides to perform an electroencephalogram (EEG) to further investigate any abnormal electrical activity in the brain that might have precipitated the seizure. The EEG results show a mild irregularity in the temporal lobe, which is consistent with the patient's reported sensation of déjà vu prior to the episode. However, the findings are not overly alarming and do not suggest any immediate, severe pathology. To ensure a comprehensive understanding of the patient's condition, a magnetic resonance imaging (MRI) scan of the brain is also ordered. The MRI results return normal, showing no structural abnormalities or lesions that could explain the seizure occurrence.

As part of the continued assessment, the nursing team monitors the patient closely during her stay in the emergency department. Her vital signs remain stable: blood pressure is 118/76 mmHg, heart rate has settled to 78 beats per minute, respiratory rate is 16 breaths per minute, and oxygen saturation is 98% on room air. Throughout the observation period, the patient remains seizure-free and exhibits no additional neurological symptoms. Taking into account the patient's stable condition and the absence of acute findings, the medical team concludes that the seizure was likely a breakthrough event in the context of chronic epilepsy, rather than a new or escalating condition.

Given these findings, the healthcare team discusses potential interventions with the patient. A slight adjustment to her lamotrigine dosage is considered to enhance seizure control, balanced with the need to minimize side effects. The patient expresses understanding and agreement with the proposed management plan. Additionally, the nursing team reinforces education on seizure precautions, medication adherence, and lifestyle modifications to help prevent future episodes. With a follow-up appointment scheduled with her neurologist, the patient is discharged with instructions to seek immediate medical attention if any concerning symptoms occur.

Section 3

Following the patient's discharge, she adheres to the adjusted lamotrigine regimen and remains vigilant with her medication schedule. Over the next few days, she experiences no further seizures and reports feeling more energetic and alert. However, during a routine follow-up call from the nursing team, the patient mentions experiencing mild dizziness and a slight rash on her forearms. These symptoms prompt a further evaluation to ensure the new dosage is well-tolerated. The nurse advises the patient to come in for a brief assessment and lab work to rule out any adverse drug reactions.

Upon examination, the patient's vital signs continue to be stable: blood pressure is 116/74 mmHg, heart rate is 80 beats per minute, respiratory rate is 18 breaths per minute, and oxygen saturation is 97% on room air. The rash is localized and non-blistering, and the patient denies any itching or swelling. Blood tests are ordered to check for any abnormalities in liver function or electrolyte imbalances that could be related to the medication adjustment. The results show slightly elevated liver enzymes, which, while not immediately concerning, warrant close monitoring. The healthcare team discusses these findings with the patient, emphasizing the importance of ongoing observation and potential further adjustments to her treatment plan.

The patient is reassured by the thoroughness of the follow-up care and agrees to weekly check-ins with her healthcare provider to monitor her symptoms. The nurse reviews the signs of serious side effects that would require prompt medical attention, such as a widespread rash or jaundice. With these precautionary measures in place, the patient feels confident in managing her condition and continues to engage in activities that support her overall wellbeing. This collaborative approach underscores the importance of patient education and proactive management in preventing complications while optimizing seizure control.

Section 4

A week after the initial follow-up, the patient arrives for her scheduled check-in, feeling optimistic but still experiencing mild dizziness and the localized rash. During the assessment, the nurse notes that the rash has not spread and remains non-blistering. The patient continues to deny any itching, discomfort, or other systemic symptoms, such as fever or malaise. Her vital signs remain stable, with a blood pressure of 114/76 mmHg, heart rate of 78 beats per minute, respiratory rate of 16 breaths per minute, and oxygen saturation of 98% on room air. Although her dizziness remains mild, the patient reports that it occasionally affects her balance, particularly when standing up quickly.

To further investigate these symptoms, the healthcare team orders additional lab work, including a comprehensive metabolic panel and a complete blood count, to pinpoint any underlying issues that may contribute to her dizziness and rash. The new lab results reveal that her liver enzymes, while still slightly elevated, have not increased further, suggesting a stable situation that requires continued monitoring. Her electrolyte levels are within normal ranges, and her blood count shows no signs of infection or anemia that might explain her dizziness.

With these findings, the team decides to maintain the current lamotrigine dosage while implementing supportive measures to address her symptoms. The nurse educates the patient on strategies to manage dizziness, such as rising slowly from seated positions and ensuring adequate hydration. Additionally, the nurse discusses the importance of protecting her skin from irritants and monitoring the rash for any changes. The patient feels reassured by the proactive approach and agrees to return for another follow-up in two weeks to reassess her condition and ensure ongoing stability. This careful monitoring and patient involvement highlight the importance of individualized care plans in managing medication side effects without compromising seizure control.

Section 5

Two weeks later, the patient returns for her follow-up appointment, eager to report on her progress. During the initial assessment, the nurse observes that the localized rash has started to fade, with no new areas of involvement. The patient confirms that she has been diligent in protecting her skin from potential irritants and monitoring for any changes, which seems to have contributed positively to the resolution of the rash. Her vital signs remain stable, with a blood pressure of 116/78 mmHg, heart rate of 80 beats per minute, respiratory rate of 16 breaths per minute, and oxygen saturation of 98% on room air.

The patient reports that her dizziness has slightly improved with the implementation of the strategies discussed during the last visit. She mentions that by taking care to rise slowly from seated positions and maintaining adequate hydration, she experiences fewer episodes of dizziness and improved balance. Encouraged by this progress, the healthcare team decides to continue the current lamotrigine dosage and supportive care measures, emphasizing the importance of adherence to both medication and lifestyle adjustments.

Recognizing the need for ongoing monitoring, the nurse schedules another follow-up in a month and advises the patient to reach out should any new symptoms arise. The case continues to illustrate the efficacy of individualized care plans and patient education in managing minor complications associated with seizure medications, reinforcing the role of proactive engagement in achieving optimal health outcomes. This ongoing collaboration between the patient and healthcare team ensures that the patient's seizure control remains uncompromised while addressing and alleviating any side effects effectively.